Tải xuống
Tóm tắt
ABSTRACT
Background: Anti-N-methyl-D-aspartate receptor encephalitis is a rare autoimmune disease characterized by severe neurological and psychiatric symptoms and difficult to diagnose. We report a case of Anti-N-methyl-D-aspartate receptor encephalitis diagnosed at the Pediatric Center of Hue Central Hospital.
Case report: A 3½ - year - old girl with previously normal psychomotor development developed behavioral problems and speech impairment 2 week ago. From the onset of symptoms, choreic movements gradually appeared. Hematological, neuroradiological, and neurological examinations were negative; however, her symptoms worsened and treatment with methylprednisone was started. Although her choreic movements improved, her neuropsychological and behavioral symptoms still continued. Anti-N-methyl-D-spartate receptor antibodies in cerebrospinal fluid were detected. The second dose of methylprednisone and then immunoglobulins was administered. After several weeks of treatment, she was well recovered with a progressive improvement in language and behavior.
Conclusions: Anti-N-methyl-D-aspartate receptor encephalitis in pediatric patients can present initially
with neuropsychological and behavioral symptoms.
Tài liệu tham khảo
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| Đã xuất bản | 24-01-2025 | |
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| Số tạp chí | Số 72 (2021) | |
| Phân mục | Báo cáo trường hợp | |
| DOI | 10.38103/jcmhch.2021.72.3 | |
| Từ khóa | Keywords: Anti-N-methyl-D-aspartate receptor, encephalitis, choreic movement |
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