Measles outbreak in pediatric oncology patients at Hue central hospital, Vietnam

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ABSTRACT
Background: Measles outbreaks in immunocompromised population is a big challenge to interrupt endemic transmission. This study aimed to investigate of measles in pediatric oncology patients and find the reason behind the outbreak.
Methods: A descriptive and prospective study on 11 paediatric oncology patients with measles. We collected demographic, epidemiological, and clinical data. Most of suspected measles cases were done measles IgM test and clinical data were followed up and analysed by Medcalc software.
Results: From April 20 to July 10 in 2019, a total of 11 patients with malignancies were notified to develop measles in Hue. Of these 11 patient with the median age of 4.0 years (range: 1 year to 9 years), 2 (18.2%) hadn’t received any dose of measles vaccine, 5 (45.5%) received 2 doses and 4 (36.4%) had received 1 dose of measles vaccine; all patients had fever with the median fever of 39 degrees Celsius (range: 38.5 – 39.5), the median fever duration was 7 days, 100% had cough and rash, 3 (27.3%) had pneumonia complication, 2 (18.2%) had elevated liver transaminase level. All patients had hospital visits or were hospitalized before measles onset, with the median time: 10 days (range: 7-24 days), all patients were likely to exposed each other. 100% patient recovered.
Conclusions: Children with cancer is very easy to exposed measles to each other. Getting vaccinated is the best way to prevent measles, and improved infection control was crititcal for the prevention of measles in malignancy patients.

Tài liệu tham khảo

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Đã xuất bản 24-01-2025
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Ngôn ngữ
Số tạp chí Số 56 (2019)
Phân mục Nghiên cứu
DOI
Từ khóa Key words: Children; Measles; Oncology.

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Bản quyền (c) 2019 Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế

Hoa, N. T. K., Hao, T. K., Cuc, T. T. K., Yen, T. T. K., & Son, N. H. (2025). Measles outbreak in pediatric oncology patients at Hue central hospital, Vietnam. Tạp Chí Y học lâm sàng Bệnh viện Trung Ương Huế, (56), 36–40. Truy vấn từ https://jcmhch.com.vn/index.php/home/article/view/689