Tải xuống
Tóm tắt
Meningoencephalitis is not a rare disease in children. However, eosinophilic meningitis due to
Angiostrongylus cantonensis is unusual in pediatric population. We describe the case of a 12-year-old girl
from central zone of Vietnam with eosinophilic meningitis. The patient lived in a rural area, where farming
is widespread, and presented with fever and headache. Laboratory results showed peripheral eosinophilia,
cerebrospinal fluid white blood cell count 730/mm3 with many of eosinophils, cerebrospinal fluid ELISA
positive for Angiostrongylus cantonensis, and blood ELISA positive for A. cantonensis. The presentation
was consistent with a diagnosis of A. cantonensis eosinophilic meningitis. The patient recovered fully after
administering albendazole (800 mg/day for 2 weeks), and intravenous dexamethasone (0.6 mg/kg/day
every 8 hours) and mannitol (1.5 g/kg/day every 8 hours) for the first 3 days, followed by 5 days of oral
prednisolone (2 mg/kg/day).
Keywords: Angiostrongylus cantonensis, eosinophilic meningitis, children
Tài liệu tham khảo
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Qvarnstrom Y, Xayavong M, da Silva AC, Park SY, Whelen AC, Calimlim PS, et al. Real-Time Polymerase Chain Reaction Detection of Angiostrongylus cantonensis DNA in Cerebrospinal Fluid from Patients with Eosinophilic Meningitis. Am J Trop Med Hyg 2016;94:176-81
Sawanyawisuth K, Sawanyawisuth K. Treatment of angiostrongyliasis. Trans R Soc Trop Med Hyg 2008;102:990-6
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Tseng YT, Tsai HC, Sy CL, Lee SS, Wann SR, Wang YH, et al. Clinical manifestations of eosinophilic meningitis caused by Angiostrongylus cantonensis: 18 years’ experience in a medical center in southern Taiwan. J Microbiol Immunol
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Lee IC. Angiostrongylus cantonensis meningitis in two developmentally delayed children: findings in brain images. Pediatr Infect Dis J 2010;29:90-1
Jin EH, Ma Q, Ma DQ, He W, Ji AP, Yin CH. Magnetic resonance imaging of eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis following eating freshwater snails. Chin Med J (Engl) 2008;121:67-72
Tsai HC, Tseng YT, Yen CM, Chen ER, Sy CL, Lee SS, et al. Brain magnetic resonance imaging abnormalities in eosinophilic meningitis caused by Angiostrongylus cantonensis infection. Vector Borne Zoonotic Dis 2012;12:161-6
Tsai HC, Lai PH, Sy CL, Lee SS, Yen CM, Wann SR, et al. Encephalitis caused by Angiostrongylus cantonensis after eating raw frogs mixed with wine as a health supplement. Intern Med 2011;50:771-4
Diao Z, Chen X, Yin C, Wang J, Qi H, Ji A. Angiostrongylus cantonensis: effect of combination therapy with albendazole and dexamethasone on Th cytokine gene expression in PBMC from patients with eosinophilic meningitis. Exp Parasitol 2009;123:1-5
Li YC, Hu XM, Tong CJ, Liu J, Li MT, Wang SQ. [Investigation on serology, risk factor and awareness of angiostrongylus cantonensis in Hainan province]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 2011;29:74-5
| Đã xuất bản | 15-01-2025 | |
| Toàn văn |
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| Ngôn ngữ |
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| Số tạp chí | Số 69 (2021) | |
| Phân mục | Báo cáo trường hợp | |
| DOI | 10.38103/jcmhch.2021.69.17 | |
| Từ khóa | Meningoencephalitis is not a rare disease in children. However, eosinophilic meningitis due to Angiostrongylus cantonensis is unusual in pediatric population. We describe the case of a 12-year-old girl from central zone of Vietnam with eosinophilic meningitis. The patient lived in a rural area, where farming is widespread, and presented with fever and headache. Laboratory results showed peripheral eosinophilia, cerebrospinal fluid white blood cell count 730/mm3 with many of eosinophils, cerebrospinal fluid ELISA positive for Angiostrongylus cantonensis, and blood ELISA positive for A. cantonensis. The presentation was consistent with a diagnosis of A. cantonensis eosinophilic meningitis. The patient recovered fully after administering albendazole (800 mg/day for 2 weeks), and intravenous dexamethasone (0.6 mg/kg/day every 8 hours) and mannitol (1.5 g/kg/day every 8 hours) for the first 3 days, followed by 5 days of oral prednisolone (2 mg/kg/day). Keywords: Angiostrongylus cantonensis, eosinophilic meningitis, children |
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