Effects of propofol for repeated prolonged deep sedation in pediatric patients undergoing radiotherapy in oncology centre of Hue central hospital

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ABSTRACT

Objective: Immobilization of pediatric patients undergoing radiotherapy (RT) often requires anaesthesia. The aim of this study is to evaluate the safety and sufficiency of a propofol injection for repeated prolonged deep sedation in pediatric patients for RT.

Patients and methods: Patients who underwent anesthesia for RT between March 2014 and June 2016 were included in the study. Sedation was introduced with a repeated small boluses of intravenous propofol 0.045 mg.kg-1 until unconsciousness and inactivity occurred. When unwanted movement was observed, an additional dose of propofol was administered. We assessed the patient characteristics, oncologic diagnosis, duration of sedation, sedation scores and complications related to sedation.

Results: Total 136 sedative anaesthetics performed in 9 consecutive paediatric oncology patients, mean age 38.6 (8.0) months (range 30-54). A loading dose of 3.3 (0,4) mg.kg-1 propofol was administered for induction. Patients breathed spontaneously and do not have unwanted movements during the radiation procedure. Mean duration of sedation was 6.9 (0.7) mins. Mean awakening time was 8,1 (2,0) mins and could be discharged about 30 mins later. There was no clinical important complication of involving respiration, circulation or neurology during and after sedation.

Conclusion: Deep sedation with propofol seems to be an excellent method to immobilize paediatric patients during RT procedures.

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Đã xuất bản 24-01-2025
Toàn văn
pdf (English)     3    1
Ngôn ngữ
Số tạp chí Số 56 (2019)
Phân mục Nghiên cứu
DOI
Từ khóa Keywords: Sedation, pediatric, radiotherapy, propofol.

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công trình này được cấp phép theo Creative Commons Attribution-phi thương mại-NoDerivatives 4.0 License International .

Bản quyền (c) 2019 Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế

Binh, L. N., Oanh, T. T. T., Trinh, H. T. D., & Nguyen, T. T. N. (2025). Effects of propofol for repeated prolonged deep sedation in pediatric patients undergoing radiotherapy in oncology centre of Hue central hospital. Tạp Chí Y học lâm sàng Bệnh viện Trung Ương Huế, (56), 19–24. Truy vấn từ https://jcmhch.com.vn/index.php/home/article/view/676