Abstract

ABSTRACT

Objectives: Yolk sac (endodermal sinus) tumor arising primarily from vagina is extremely rare, which has no published standardized management approach. We present a case of yolk sack tumor of vagina, in which we directed a special attention towards chemotherapy along with an appropriate surgical approach to remove the tumor and preserve sexual and reproductive function.

Case study: Report a case of a vaginal yolk sac tumor in a 7-month-old female infant who was admitted to hospital with history of vaginal bleeding. Serum alpha-fetoprotein, computed tomography and pathologic biopsy samples confirmed a vaginal yolk sac tumor. The patient was given six cycles of chemotherapy along with vaginoscopic-assisted tumor resection and continued to follow up. After 8 months treatment and following up, the AFP level increased again and radiography showed the recurrent tumor. The patient was taken to surgery, where completely tumor resection was done through perineal approach. AFP returned to normal level after surgery.

Conclusion: Perineal approach appears to besimple and efficient to remove the tumor in vagnial position, which enable to preserve patient’s reproductive anatomy and function.