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Abstract
Objective: This study aims to assess the effectiveness and safety of acupressure massage in the treatment of chemotherapy - induced peripheral neuropathy (CIPN) in Hue Central Hospital.
Methods: This study was a pilot randomized controlled trial. 70 participants with CIPN were randomly assigned (1:1) to receive five sessions of acupressure massage (30 minutes each session for 5 day) or take two 300mg capsules gabapentin per day for five days. The main endpoint was CIPN sympton severity measured by the patient neurotoxicity questionnaire (PNQ) and Common Terminology Criteria for Adverse Events (CTCAE).
Results: The PNQ (item 1 & 2) and CTCAE sensory neuropathy grading scales decreased significantly over time in both groups (both p < 0.01), with a significantly higher reduction in the acupressure massage group (-0.97 ± 0.62, - 0.66 ± 0.11 and -0.34 ± 0.54, respectively). In addition, the acupressure massage group showed a higher safety effect than the gabapentin group, with no side effects.
Conclusion: The acupressure massage therapy gives a good result of treatment for CIPN, without any side effect.
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| Published | 07-01-2025 | |
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| Issue | No. 79 (2022) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.79.16 | |
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