Characteristics of venous thromboembolism among older adults with cancer at geriatrics and palliative care department, university medical center at Ho Chi Minh city

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Abstract

CHARACTERISTICS OF VENOUS THROMBOEMBOLISM AMONG OLDER ADULTS WITH CANCER AT GERIATRICS AND PALLIATIVE CARE DEPARTMENT, UNIVERSITY MEDICAL CENTER AT HO CHI MINH CITY

Objective: This study aimed to assess the prevalence and clinical, paraclinical features of VTE in older adults with diagnosis of cancer at Geriatrics and Palliative care department in University Medical Center at Ho Chi Minh city.

Methods: A retrospective study was conducted in 1,167 medical records of older inpatients (≥ 60 years old) with diagnosis of cancer, at Geriatrics and Palliative care department in UMC, from 01/01/2016 to 31/12/2020. Data on demographic, social, clinical aspects, treatments and adverse effects were collected.

Results: The prevalence of older adults having cancers was 12.9% (151), with 3,8% (44) of deep VTE of the lower extremities and 3,9% (46) of pulmonary embolism. Infection, hypertension, chronic kidney disease and diabetes type 2 were the most common comorbidities. Liver, lung and colorectal cancers were the most popular cancer. Among deep VTE of the lower extremity clinical symptoms, leg swelling (61.3%) and footsore (59%) were the most common, while the prevalence of deep VTE of left leg was higher (56.8%). In addition, dyspnea (80.4%) and tachycardia (71.7%) are the most popular symptoms of pulmonary embolism.

Conclusions: The prevalence of VTE was high in clinical practice. Therefore, doctors should pay attention in order to have strategies for prevention during hospital stay. However, clinical, paraclinical features of VTE were atypical and nonspecific. In practice, doctors should evaluate the risk factors of VTE and choose suitable scoring measurement to have appropriate strategies.

https://doi.org/10.38103/jcmhch.90.9

References

Ban chỉ đạo tổng điều tra dân số và nhà ở Trung Ương. Kết

quả tổng điều tra dân số và nhà ở thời điểm 0 giờ ngày 01

tháng 4 năm 2019. Nhà xuất bản Thống Kê (12/2019).

Pilleron S, SotoPerez-de-Celis E, Vignat J, et al. Estimated

global cancer incidence in the oldest adults in 2018 and

projections to 2050. International journal of cancer.

;148(3):601-8.

Abdol Razak NB, Jones G, Bhandari M, et al. Cancerassociated thrombosis: an overview of mechanisms, risk

factors, and treatment. Cancers. 2018;10(10):380.

Wang H, Xu X, Pu C, et al. Clinical characteristics and

prognosis of cancer patients with venous thromboembolism.

Journal of cancer research and therapeutics. 2019;15(2):344.

Marks MA, Engels EA. Venous Thromboembolism and

Cancer Risk among Elderly Adults in the United StatesVenous

Thromboembolism and Cancer Risk. Cancer epidemiology,

biomarkers & prevention. 2014; 23(5):774-83.

Aleem A, Diab AR, Alsaleh K, et al. Frequency, clinical

pattern and outcome of thrombosis in cancer patients in

Saudi Arabia. Asian Pacific Journal of Cancer Prevention.

;13(4): 1311-5.

Đặng Vạn Phước, Phạm Gia Khải, Nguyễn Lân Việt và

cộng sự. Huyết khối tĩnh mạch sâu: Chẩn đoán bằng siêu

âm Dupplex trên bệnh nhân nội khoa nằm viện. Tạp chí Tim

mạch học Việt Nam. 2010:56:24 - 36.

Meyer HJ, Wienke A, Surov A. Incidental pulmonary

embolism in oncologic patients a systematic review

and meta-analysis. Supportive Care in Cancer.

;29(3):1293-302.

Đỗ Minh Hiền. Nhận xét đặc điểm lâm sàng, cận lâm sàng

của bệnh nhân ung thư có huyết khối tĩnh mạch sâu các chi

và kết quả điều trị, Luận văn thạc sĩ y học. Đại học Y Hà

Nội. 2019.

Imberti D, Agnelli G, Ageno W, et al. Clinical characteristics

and management of cancer - associated acute venous

thromboembolism: findings from the MASTER Registry.

Haematologica. 2008;93(2):273-8.

Nguyễn Thị Tuyết Mai, Trần Thị Xuân Anh, Bùi Thế Dũng

và cộng sự. Đặc điểm lâm sàng và cận lâm sàng và kết quả

điều trị thuyên tắc phổi do huyết khối tại bệnh viện Đại học

Y Dược thành phố Hồ Chí Minh. Tạp chí Y học thành phố

Hồ Chí Minh. 2019;23 (2):208 - 213.

Nguyễn Văn Tân, Nguyễn Đức Thành, Nguyễn Ngọc

Phương Dung. Đặc điểm lâm sàng và cận lâm sàng của

bệnh nhân cao tuổi thuyên tắc phổi tại bệnh viện Thống

Nhất. Tạp chí Y học thành phố Hồ Chí Minh. 2018;22

(1):224-230.

Lê Thượng Vũ. Giá trị của X-quang ngực trong chẩn đoán

thuyên tắc phổi. Tạp chí Y học thành phố Hồ Chí Minh.

;14(4):444-450.

Mok KH, Wong SW, Wong YM, et al. Clinical characteristics,

risk factors and outcomes of South - East Asian patients

with acute pulmonary embolism. International Journal of

Cardiology. 2017;249:431-443

Published 28-12-2024
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Issue No. 90 (2023)
Section Original article
DOI 10.38103/jcmhch.90.9
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Copyright (c) 2023 Journal of Clinical Medicine Hue Central Hospital

Nguyen Ngoc Hoanh My Tien, Trinh Thi Bich Ha, & Nguyen Thi Phuong Lan. (2024). Characteristics of venous thromboembolism among older adults with cancer at geriatrics and palliative care department, university medical center at Ho Chi Minh city. Journal of Clinical Medicine Hue Central Hospital, (90), 60–66. https://doi.org/10.38103/jcmhch.90.9