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Abstract
Background: Acute coronary syndrome is a public health problem. NT-ProBNP, used popularly as a tool for diagnosing acute heart failure caused by myocardial infarction, especially relates to short-term prognosis in non-ST elevtion myocardial infarction patients. Besides prognosis scores like TIMI and GRACE, biomarkers such as hs-Troponin T and NT-ProBNP are novel tools in evaluating prognosis in acute coronary syndrome, in general, and in non-ST elevation myocardial infarction nowadays.
Objectives: - Stratificating risk factors and evaluating the prognosis of patients based on GRACE scores - Evaluating the correlation between NT-ProBNP, hs-Troponin T and the clinical severity, coronary artery lesions and cardiac events within 30 days Subjects: Patients diagnosed with non-ST elevation myocardial infarction Methods: Cross-sectional, longitudinal study
Results: Serum hs-Troponin T and NT-ProBNP concentration increases with degree of risk of GRACE score, p>0,05. Serum hs-Troponin T and NT-ProBNP concentration has strong relation with the hospital admission time, p <0,01. Serum and NT-ProBNP concentration increases with the degree of angina, p<0,05. Serum hs-Troponin T and NT-ProBNP concentration increases with degree of NYHA heart failure, p<0,05. Serum hs- Troponin T and NT-ProBNP concentration proportionally increases with the number and degree of injured coronary arteries, cardiac events within 30 days, p<0,01.
Conclusion: Serum hs-Troponin T and NT-ProBNP concentration increases with GRACE score, the degree of NYHA heart failure, proportionally increases with the number and severity of injured coronary arteries, cardiac events within 30 days.
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| Published | 27-04-2021 | |
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| Issue | No. 68 (2021) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.2021.68.3 | |
| Keywords | NMCT không ST chênh, GRACE, hs-Troponin T và NT-proBNP Non-ST elevation MI, GRACE, hs-Troponin T and NT-proBNP |
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