Tóm tắt

Objectives: To evaluate the efficacy and safety of Chitosan-based hemostatic dressing (Hemoseal®) for femoral artery access closure after cardiovascular interventions at Hanoi Heart Hospital.

Methods: A cross-sectional descriptive study was conducted on 270 patients undergoing cardiovascular interventions via femoral access from February 2024 to July 2025. Hemoseal® dressing were applied for hemostasis following sheath removal. The primary outcomes were mean time to hemostasis and technical success rate. Secondary outcomes included the incidence of local complications such as hematoma, re-bleeding, pseudoaneurysm, or arterial occlusion.

Results: The mean age was 58.47 ± 15.31 years. The average time to hemostasis was 8.45 ± 1.46 minutes. The technical success rate was 90% initially and reached 100% secondary, with an overall clinical success rate of 98.1%. Local complication rate was 1.8%, consisting of minor hematoma (1.1%) and re-bleeding (0.7%), with no major complications reported. Hemostatic efficacy was consistent regardless of age, comorbidities, or coagulation profiles.

Conclusions: Hemoseal® is an effective and safe hemostatic solution that significantly reduces hemostasis time, medical staff workload, and enhances patient comfort compared to conventional manual compression.