Downloads
Abstract
Purpose: To describe the characteristic imaging of thyroid cancer on computed tomography and compare with the surgical and histopathologic findings in order todetermine the role of computed tomography in evaluation of invasion and regional lymph nodes metastasis on patients with thyroid cancer.
Methods: All patients with a clinical diagnosis of thyroid cancer underwent CT, had surgery with full reports and had histopathologically confirmed malignant lesions in the thyroid gland. Descriptive cross - sectional study design. CT scanning was performed using Optima 660 (GE Healthcare, USA) and Bright Speed Elite (GE Healthcare, USA) in Ho Chi Minh City Oncology Hospital. Comparison of CT features with surgical and pathological results.
Results: The features of thyroid cancer on CT include irregular margin, unclear boundary, calcification and strong contrast enhancement. The lesions in the study were mainly > 40mm in size with the rate of 35.4%. Thyroid cancer that invades the capsule and strap muscles is more common than the trachea and esophagus and is less common with blood vessels and subcutaneous soft tissue. There were no mediastinal invasion lesions in our study. The rate of lymph nodes metastasis in thyroid cancer is high and the central compartment lymph nodes predominates.
Conclusion: CT can be a high valuable tool for evaluation of invasive thyroid cancer and the lymph nodes metastasis.
References
Hyuna S., Jacques F., Rebecca L.S., Mathieu L., Isabelle S., Ahmedin J.D., et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. American Cancer Society Journals. 2021;71:212-236.
Bryan R.H, Erik K.A., Keith C.B., Gerard M.B., Susan J.M., Yuri E.N., et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26:1-133.
Michael W.Y., Andrew J.B., Victor A.B., Robert L. Ferris, Laurie A. Loevner, Susan J. Mandel, et al. American Thyroid Association Statement on Preoperative Imaging for Thyroid Cancer Surgery. Thyroid. 2015;25:3-14.
Asako M., Robert W.D., Yoshimi A. Magnetic Resonance Imaging of Thyroid Cancer. Topics in Magnetic Resonance Imaging. 2007;18:293-302.
C.H. Suh, J.H. Baek, Y.J. Choi, Lee JH. Performance of CT in the Preoperative Diagnosis of Cervical Lymph Node Metastasis in Patients with Papillary Thyroid Cancer: A Systematic Review and Meta-Analysis. American Journal of Neuroradiology. 2016;38:154-161.
Ji E.A., Jeong H.L., Jong S.Y., Young Ki Shong, Seok Joon Hong, Deok Hee Lee, et al. Diagnostic Accuracy of CT and Ultrasonography for Evaluating Metastatic Cervical Lymph Nodes in Patients with Thyroid Cancer. World Journal of Surgery. 2008;32:1552-1558.
Ramundo V., Lamartina L., Falcone R., Ciotti L., Lomonaco C., Biffoni M., et al. Is thyroid nodule location associated with malignancy risk? Ultrasonography (Seoul, Korea). 2019;38:231-235.
Fengyan Z., Ying Q., Z. H. Value of CT Features in the Diagnosis of Papillary Thyroid Tumors in Incidental Thyroid Nodules. International Journal of Endocrinology. 2020;2020:1-7.
Klubo-Gwiezdzinska J., Manes RP, Chia SH, Burman KD, Stathatos NA, Deeb ZE, et al. Ectopic Cervical Thyroid Carcinoma - Review of the Literature with Illustrative Case Series. The Journal of Clinical Endocrinology & Metabolism. 2011;96:2684-2691.
Lianos G., Bali C., Tatsis V., Anastasiadi Z., Lianou E., Papathanasiou V., et al. Ectopic thyroid carcinoma. Case report. Il Giornale di chirurgia. 2013;34:114-116.
Cramer JD., Fu P., Harth KC., Margevicius S., Wilhelm SM. Analysis of the rising incidence of thyroid cancer using the Surveillance, Epidemiology and End Results national cancer data registry. Surgery. 2010;148:1147-1153.
Wu CW., Dionigi G., Lee KW., Hsiao PJ., Paul Shin MC., Tsai KB., et al. Calcifications in thyroid nodules identified on preoperative computed tomography: Patterns and clinical significance. Surgery. 2012;151:464-470.
Chung SR., Baek JH., Choi YJ., Sung TY., Song DE., Kim TY., et al. Sonographic Assessment of the Extent of Extrathyroidal Extension in Thyroid Cancer. Korean Journal of Radiology. 2020;21:1187-1195.
Lee DY., Kwon TK., Sung MW., Kim KH., Hah JH. Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography. International Journal of Endocrinology. 2014;2014:1-6.
Liu L., Oh C., Heo JH., Park HS., Lee K., Chang JW., et al. Clinical significance of extrathyroidal extension according to primary tumor size in papillary thyroid carcinoma. European Journal of Surgical Oncology (EJSO). 2018;2018:1-6.
Li G., Li R., Song L., Chen W., Jiang K., Tang H., et al. Implications of Extrathyroidal Extension Invading Only the Strap Muscles in Papillary Thyroid Carcinomas. Thyroid. 2020;30:57-64.
Rosario PW., Mourão G., Calsolari MR. Risk of recurrence in patients with papillary thyroid carcinoma and minimal extrathyroidal extension not treated with radioiodine. Journal of Endocrinological Investigation. 2018.
Jin BJ., Kim MK., Ji YB., Song CM., Park JH., Tae K. Characteristics and significance of minimal and maximal extrathyroidal extension in papillary thyroid carcinoma. Oral Oncology. 2015;51:759-763.
Seo YL., Yoon DY., Lim KJ., Ji Hyeon Cha., Eun Joo Yun., Chul Soon Choi, et al. Locally Advanced Thyroid Cancer: Can CT Help in Prediction of Extrathyroidal Invasion to Adjacent Structures? American Journal of Roentgenology. 2010;195:W240-W244.
Kim H., Kim JA., Son EJ., Youk JH., Chung TS., Park CS., et al. Preoperative prediction of the extrathyroidal extension of papillary thyroid carcinoma with ultrasonography versus MRI: A retrospective cohort study. International Journal of Surgery. 2014;12:544-548.
Ibrahimpasic T., Ghossein R., Carlson DL., Chernichenko N., Nixon I., Palmer FL., et al. Poorly Differentiated Thyroid Carcinoma Presenting with Gross Extrathyroidal Extension: 1986–2009 Memorial Sloan-Kettering Cancer Center Experience. Thyroid. 2013;23:997-1002.
Lee DW., Ji YB., Sung ES., Park JS., Lee YJ., Park DW., et al. Roles of ultrasonography and computed tomography in the surgical management of cervical lymph node metastases in papillary thyroid carcinoma. European Journal of Surgical Oncology (EJSO). 2013;39:191-196.
| Published | 20-01-2023 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | No. 84 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.84.17 | |
| Keywords | Cắt lớp vi tính, ung thư tuyến giáp, phẫu thuật, giải phẫu bệnh, giai đoạn Computed tomography, thyroid cancer, surgegy, pathology, staging |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Journal of Clinical Medicine Hue Central Hospital