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Abstract
Aim: To evaluate the safety and effectiveness of percutaneous transhepatic biliary drainage (PTBD) for malignant biliary obstruction.
Methods: A cross - sectional study was conducted on 48 patients with malignant biliary obstruction who underwent PTBD at Hue University of Medicine and Pharmacy Hospital from 1/2019 to 10/2021. Indications, technique, safety and effectiveness of PTBD were based on the Society of Interventional Radiology (SIR) guideline. Study endpoint was the successful placement of the drainage catheter within the biliary tract. A post PTBD reduction of total bilirubin level ≥20% was defined significant. Catheter position, configuration and side-hole modification were decided case - by - case based on cholangiographic findings and treatment purposes. Results: The mean age was 66.4 ± 13.3 years. The mean total bilirubin level was 235.25±129.87 μmol/l. PTBD was indicated as a first-line modality in 89.6%, mostly for palliative purpose (89.6%); 10.4% in emergency setting. Technical success was 100%, 37.5% achieved internal - external drainage. Significant reduction in serum total bilirubin in 78.9% of cases. Multifocal liver lesions were associated with reduced drainage outcome. In - hospital major and minor complication rates were 12.5% and 18.8%, respectively. All major complications were infection - related.
Conclusions: PTBD is safe and effective for the management for malignant biliary obstruction.
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| Published | 12-01-2025 | |
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| Issue | No. 77 (2022) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.77.9 | |
| Keywords | Tắc mật ác tính, dẫn lưu đường mật qua da, bilirubin malignant biliary obstruction, percutaneous transhepatic biliary drainage, bilirubin |
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