Downloads
Abstract
Background: For breast cancer, radiation therapy is an essential adjuvant treatment to help reduce local
recurrence and increase survival. However, radiation therapy has adverse effects on the cardiovascular
systemespecially for left breast cancer. Several studies have demonstrated that cardiovascular morbidity
and mortality increase in proportion to the mean cardiac dose. New radiotherapy techniques in radiation
therapy for left breast cancer help optimize dose to radiation volume and better protect healthy organs,
which requires high accuracy when patient set - up. Errors due to equipment or patient set - up will lead
to the risk of overdosage or underdosage and risk of relapse. Therefore, radiation therapy requires high precision throughout the process from simulation to planning and conducting radiation therapy. Radiation
therapy for left breast cancer combined with Deep Inspiration Breath - hold (DIBH) and Optical Surface
Management System (OSMS)causes the heart to move further away from the breast and chest wall during
radiation therapy, helping to reduce the cardiac dose significantly, still ensuring the radiation dose to the
target volume. The advantage of OSMS is that in addition to being applied for fastpatient set - up, without
tattooing on the skin, it also provides real - time monitoring during the entire treatment process. When the
patient’s breathing rate exceeds a certain threshold (0,3cm) the radiation beam is turned off to prevent
toxicity. Therefore, understanding and understanding the benefits of patient set - up helps to achieve
treatment goals, while reducing patient set - up time for more comfort, reducing pressure on the number of
patients, especially for patients large radiotherapy center
References
Group EBCTC. Effect of radiotherapy after
breast-conserving surgery on 10 - year
recurrence and 15 - year breast cancer death:
meta - analysis of individual patient data
for 10 801 women in 17 randomised trials.
LANCET. 2011. 378: 1707-1716.
Early Breast Cancer Trialists’ Collaborative
Group (EBCTCG) MP, Taylor C et al Effect
of radiotherapy after mastectomy and axillary
surgery on 10 - year recurrence and 20 - year
breast cancer mortality: meta - analysis of
individual patient data for 8135 LANCET. 2014.
(9935): 2127-2135.
NCI. The Surveillance, Epidemiology and End
Results (SEER) Cancer Registries Breast Cancer
Statistics Review 1975-2015. N.C.I. 2016: 13.
Thomas A, et al. Incidence and Survival Among
Young Women With Stage I-III Breast Cancer:
SEER 2000- 2015. JNCI Cancer Spectr. 2019. 3: 40.
Leonard KLaDEW. Cardiotoxicity Associated
with Radiation for Breast Cancer. Toxicities of
Radiation Treatment for Breast Cancer. 2019:
-144.
Darby SC, et al. Risk of ischemic heart disease
in women after radiotherapy for breast cancer. N
Engl J Med. 368: 987-98.
Sardaro A, et al. Radiation-induced cardiac
damage in early left breast cancer patients: risk
factors, biological mechanisms, radiobiology,
and dosimetric constraints. Radiother Oncol.
103: 133-42.
Jennifer R. Bellon JSW, Shannon M. MacDonald.
Radiation Techniques and Treatment Planning
for Breast cancer. Practical Guides in Radiation
Oncology. 2016: 79.
Brahme PN, and B. Skatt. D laser camera
foraccurate patient positioning, collision
avoidance, image fusionand adaptive approaches
during diagnostic and therapeuticprocedures.
301: 911-98.
Zhao F, et al. Abdominal DIBH reduces the
cardiac dose even further: a prospective analysis.
Radiat Oncol.2018. 13(1): 116.
Macrie BD, et al. A cost - effective technique
for cardiac sparing with deep inspiration-breath
hold DIBH. 2105: 31.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2021 Journal of Clinical Medicine Hue Central Hospital