Abstract
Purposes: To investigate the influence of some clinical and laboratory characteristics on the overall
survival of advanced - stage gastric cancer patients.
Methods: A retrospective case series study with 167 early - stageadvanced - stage gastric cancer
patients recruited from at oncology department, the Hospital of Hue University of Medicine and Pharmacy
and Oncology Center of Hue Central HospitalfromJanuary 2015 to December 2020. The Kaplan - Meier method was used to estimate survival, the log - rank test analyzed the relevant factors.
Results: Median age was 58.2; male/female was 2.5/1; the most common clinical symptom was
epigastric pain (78.7%); at the time of diagnosis, almost all patients had KPS 90% (50.3%); BMI index
below 18.5 (64.1%). Serum albumin < 35g/l accounting for 86.2% of patients. 89.8% of patients had distant
metastasis disease. The median survival was 11 months. Univariate analysis indicated that age, KPS,
primary tumor location, regional nodal metastasis, venous thrombosis, serum albumin level affecting on
overall survival.
Conclusions: Advanced - stage gastric cancer patients had poor survival with a median of 11 months.
Age, KPS, tumor location, regional nodal metastasis, venous thrombosis, serum albumin level influence
overall survival.
References
Sung H., Ferlay J., Siegel R.L. et al. Global
Cancer Statistics 2020: GLOBOCAN Estimates
of Incidence and Mortality Worldwide for 36
Cancers in 185 Countries. CA Cancer J Clin.
;71(3): 209-249.
Quách Thanh Hưng. Đánh giá kết quả hóa trị bước
một ung thư dạ dày giai đoạn tiến xa bằng phác đồ
ECX và EOX tại bệnh viện Bình Dân. Tạp Chí
Học TP Hồ Chí Minh. 2014;18 (1): 39-43.
Trần Vĩnh Thọ. Kết quả hóa trị ung thư dạ dày
giai đoạn tiến xa. Tạp Chí Học TP Hồ Chí Minh.
;18 (1): 589-597.
Lu Z., Lu M., Zhang X. et al. Advanced or
metastatic gastric cancer in elderly patients:
clinicopathological, prognostic factors and
treatments. Clin Transl Oncol. 2013;15(5);
-383.
Jeong J.-H., Lim S.M., Yun J.Y. et al. Comparison
of Two Inflammation-Based Prognostic Scores
in Patients with Unresectable Advanced Gastric
Cancer. Oncology. 2012;83(5), 292-299.
ter Veer E., van Kleef J.J., Schokker S. et al.
Prognostic and predictive factors for overall
survival in metastatic oesophagogastric cancer:
A systematic review and meta-analysis. Eur J
Cancer. 2018;103, 214-226.
Fanotto V., Cordio S., Pasquini G. et al. Prognostic
factors in 868 advanced gastric cancer patients
treated with second-line chemotherapy in the
real world. Gastric Cancer. 2017;20(5), 825-833.
| Published | 05-12-2021 | |
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| Issue | No. 74 (2021) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.2021.74.4 | |
| Keywords | Ung thư dạ dày, giai đoạn tiến xa, kết cục. Outcomes, advanced - stage, gastric cancer. |

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