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Abstract
Objectives: To determine the value of liver elasticity measured by Fibroscan technique in predicting esophageal varices (EV) in Child - Pugh A, B cirrhotic patients.
Methods: A cross - sectional description, performed on 80 patients with cirrhosis of Child - Pugh A, B with upper gastrointestinal endoscopy and measurement of liver elasticity by Fibroscan technique. To determine the optimal cut - off values of hepatic elastography to predict EV and high - risk EV based on ROC curve, thereby determining the sensitivity, specificity, negative predictive value, positive predictive value and AUROC.
Results: The mean value of liver elasticity measured by Fibroscan was 27.7 ± 20.6 kPa. In which, the elasticity of Child - Pugh A cirrhotic group is 23.65 ± 18.86 kPa and Child - Pugh B is 33.48 ± 21.88 kPa; The elasticity of the group without EV was 12.3 ± 5.09 kPa, the group of low - risk EV was 15.26 ± 5.09 kPa and the group of high - risk EV was 49.58 ± 18.09 kPa. Fibroscan liver elasticity was an independent factor in predicting esophagealvarices. With a cut - off point of 17.15 kPa, it was possible to predict esophageal varices with a sensitivity of 87.8%, a specificity of 88.5%, a positive predictive value of 93.4%, a negative predictive value of 70% and an AUROC of 0.891 (0.822 - 0.961). With a cut - off point of 22.25 kPa, there was a sensitivity of 83%, a specificity of 92.1%, a positive predictive value of 86% and a negative predictive value of 90.4% in predicting high - risk esophageal varices with AUROC of 0.904 (0.830 - 0.977).
Conclusion: Fibroscan liver elastography is a useful non - invasive method in predicting esophagealvarices and high - risk varices in Child - Pugh A, B cirrhotic patients.
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| Published | 20-01-2023 | |
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| Issue | No. 84 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.84.15 | |
| Keywords | Xơ gan, giãn tĩnh mạch thực quản, Fibroscan Cirrhosis, esophageal varice, Fibroscan |
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