Downloads
Abstract
Background: The term inflammatory bowel disease (IBD) is used to represent 2 distinctive disorders of idiopathic chronic intestinal inflammation: Crohn disease and ulcerative colitis. Their respective etiologies are poorly understood, and both disorders are characterized by unpredictable exacerbations and remissions. The most common time of onset of IBD is during the preadolescent/adolescent era and young adulthood. Children with very early-onset (VEO-IBD) that presents in children < 6 years of age are uncommon (about 1%), especially under 1 year of age (0.2%). Ulcerative colitis, an idiopathic chronic inflammatory disorder, is localized to the colon and spares the upper gastrointestinal tract. Disease usually begins in the rectum and extends proximally for a variable distance. When it is localized to the rectum, the disease is ulcerative proctitis, whereas disease involving the entire colon is pancolitis.
Case report: We are presenting a case of very early-onset ulcerative colitis in a 12 months old boy who presented with watery stools with blood in the stools lasting 4 months, without fever or other unusual symptoms. Diagnosis was confirmed by colonoscopy and biopsy. Treatment was thereafter started with oral corticosteroid and mesalazine. The patient is now on remission and is on regular follow up.
Conclusion: Ulcerative colitis is an idiopathic chronic inflammatory disorder of the colon. Ulcerative colitis should be suspected in children with persistent bloody diarrhea. With early diagnosis and appropriate treatment with immunosuppressive therapy, children can lead a healthy life.
References
Ronen E. Stein and Robert N. Baldassano. Inflammatory Bowel Disease. Nelson textbook of pediatrics. 21th ed. Philadelphia: W B Saunders; 2020;362:1973-87.
Ronen E. Stein and Robert N. Baldassano. Chronic Ulcerative Colitis. Nelson textbook of pediatrics. 21th ed. Philadelphia: W B Saunders; 2020;362(1):1976-81.
Dan Turner. Levine A. Escher JC. Griffiths AM. Russell RK. Dignass A. et al. Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines. Sep 2012;55(3):340-361.
Davidson S. Infatilism in ulcerative colitis. Arch Int Med. 1939;64(6):1187-96.
Helmholz HF. Chronic ulcerative colitis in childhood. Am J Dis Child. 1923;26(5):418-30.
Jang ES. Lee DH. Kim J. Yang HJ. Lee SH. Park YS et al. Age as a clinical predictor of relapse after induction therapy in ulcerative colitis. Hepato-gastroenterology. 2009;56(94-95):1304-9.
Kelsen JR. Cuffari C. Mamula P. Ulcerative colitis in children. [Online] 2019 June. Available from: URL: https://emedicine.medscape.com/article/930146-overview.
King RC. Linden AE. Pollard HM. Chronic ulcerative colitis in childhood. Arch Dis Child. 1959;34:257-261.
Lee YM. Fock KM. See SJ. Ng TM. Khor C. Teo EK. Racial differences in the prevalence of Ulcerative colitis and Crohn’s disease in Singapore. J Gastroenterol Hepatol. 200; 15(6):622-625.
NICE. Ulcerative Colitis: management. 2019;23:1-30.
Rukunuzzaman M. Karim AB. Ulcerative colitis in infancy. Saudi J Gastroenterol: official journal of the Saudi Gastroenterology Association. 2011;17(6):414-417.
Soda A. Midha V. Sood N. Bhatia AS. Avasthi G. Incidence and prevalence of ulcerative colitis in Punjab, North India. Gut. 2003;52(11):1587-1590.
Ashley F. Julee S. Lina M. Felipez. Very Early-Onset Inflammatory Bowel Disease (VEO-IBD) Presenting with Recurrent Leukocytoclastic Vasculitis Preceded by Streptococcal Pharyngitis. Case Rep Pediatr. 2021; 12: 1-4.
Bodhrun N. Rafiqul I. Sharmistha G. Nahid K L. Very early onset-inflammatory bowel disease (veo-ibd) in a three years old child: a case report. European Journal of Pharmaceutical and Medical Research. 2021;8(7):07-09.
| Published | 21-12-2024 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | Vol. 16 No. 9 (2024) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.16.9.4 | |
| Keywords | Viêm loét đại tràng, trẻ em Ulcerative colitis, pediatrics |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2024 Journal of Clinical Medicine Hue Central Hospital