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Abstract
Background: The prognostic value of sentinel lymph node biopsy mapping of tumor lymphatics for determining metastases in patients with papillary thyroid carcinoma (PTC) remains unconfirmed. In the current study, we evaluated the accuracy of sentinel node mapping in PTC using blue dye
Material and methods: 31 patients with a diagnosis of PTC were included in the study. Immediately after anaesthesia induction, 0,5-3ml patent blue was injected perinodular. Sentinel lymph nodes were detected intraoperatively using blue dye. Total thyroidectomy was performed for all patients with dissection of group VI and/or lateral of neck lymph nodes.
Results: We have 31 patients PTC using blue dye. SLNs were identified in 30 of 31 patients (96.8%),
the sensitivity, specificity, negative predictive value and false negative rate were: 90%; 100%; 95.5% và 10% respectively. The complication of those techniques were: wound fluid (6.4%), transient hypocalcemia: 19.4%. Lymph node positive were found for 32.2%, using blue dye were 29%.
Conclutions: Sentinel node mapping in papillary thyroid carcinoma using bule dye is a feasible technique with high accuracy for the detection of lymph node involvement.
Key words: Sentinel lymph node, methylene blue dye, papillary thyroid carcinoma, lymph node dissection group VI
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