Downloads
Abstract
Background: Diabetes mellitus that occurs because of chronic liver disease (CLD) is known as hepatogenous diabetes (HD). Although the association of diabetes and liver cirrhosis was described forty years ago, it was scarcely studied for long time. Its incidence is higher in CLD of viral, alcoholic. Its pathophysiology relates to liver damage, pancreatic dysfunction, interactions between hepatitis C virus (HCV) and glucose metabolism mechanisms and genetic susceptibility.
Materials and Methods: Study on 145 patients with HBV, HCV and alcoholic cirrhosis treated at Department of Gastroenterology, Hue Central Hospital from July 2018 to July 2019.
Results: The percentage of hepatogenous diabetes is 27.6%, of which diabetes in patients cirrhosis with HCV account for 35.7%; HBV cirrhosis group is 23.7% and alcoholic is 27.9%.
References
Nguyễn Hoàng Hội, Đoàn Văn Đ, Nguyễn Văn Nam (2011), “Nghiên cứu rối loạn dung nạp Glucose máu ở bnh nhân xơ gan”, Tạp chí
Y học, Bnh vin Quân Y 103.
Valavian SM et al (2004). Prevalence and determinants with chronic liver dsease. BMC endocrine disorder. 1186, m.1472.
Arao M. Murase K, Kusakabe A, Yoshiokak, Fukuzawa Y, Ishikawa T, Tagawa T, Ymannouchi KichimiyaH, SameshimaY, Kakumus. (2003),
Prevalence of diabetes mellitus in Japanese patients infected chronically with hepatitis C virus, Gastroenterol, 38 (4), pp.355-360.
Imazeki F, Ykoshuka O, Fukaik, Kanda T, KojimaH, Saisho .H. (2008), Prevalence of diabetes mellitus and insulin resistance in patients with chronic hepatitis C: comparison with hepatitis B virus infected and hepatitis C virus cleared patients, Liver, 28 (03), pp.355-362.
Decocks verslype C , Fevery J. (2007), Hepatitis C and insulin reisistance: mutural interaction. Acta, clin. Belg, 62. (2), pp.11-19.
Petrides As, Schulze-Berge D, VogtC, Matthews DE Strohmever. (1993), Pathogenesis of glucose intolerance and diabetes mellitus in cirrhosis. Hepatology, 21 (1), pp.265-266.
Henrik Toft Sorensen, Anne Martir, Thulstrup, Lene Mellemkjar, Peter Jepsen, Erik Chisteusen, Jorgen Holsen, Henrik Viltrup. (2003), Long term survival and cause specific mortality in patients with cirrhosis of liver: a nation wide cohort study in Denmark, J. of Clin. Epidemiology.
Miiller MJ. Pirlich M ,Balks HJ, Selberg. (1994), Glucose intolerance in liver cirrhosis: role of hepatic and hepatic influences, Eu J Clin
Chem Clin Biochem. 32 (10), pp.749-758.
| Published | 10-01-2025 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | No. 57 (2019) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.2019.57.1 | |
| Keywords | Từ khóa: Đái tháo đường gan, Xơ gan, Bệnh gan mạn tính, Đái tháo đường Keywords: Hepatogenous diabetes, Cirrhosis, Chronic liver disease, Diabetes mellitus |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2019 Journal of Clinical Medicine Hue Central Hospital