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Abstract
Background: COVID-19 is an acute viral infection and has affected seriously all over the world. One of the dangerous complications of COVID-19 is thrombosis. D-dimer is a reliable marker for thrombosis, the higher D-dimer level, the more serious thrombosis. Therefore, D-dimer can be used as a marker to assess and prognosticate in COVID-19 patients.
Objective: Evaluating the rate of D-dimer increase in COVID-19 patients and look for some related factor with D-dimer increase.
Methods: Cross - sectional descriptive research method. Studying 205 medical records of COVID-19 patients treated at Da Nang Hospital for Lung Diseases, Viet Nam, from 9/2021 to 4/2022.
Results: The rate of D-dimer increase in COVID-19 patients at Da Nang Hospital for Lung Diseases was 73.2%; Factors associated with D-dimer increase in COVID-19 patients included: age, history of diabetes, clinical symptoms such as fever, chest tightness, shortness of breath, fatigue, cognitive disorders (p < 0.05). Patients with D-dimer values > 638 µg/L had more severe disease (sensitivity 80.0% and specificity 90.8%); curve area AUC = 0.900.
Conclusion: D-dimer is considered as an indicator related to the severity of Covid-19
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| Published | 20-01-2023 | |
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| Issue | No. 84 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.84.11 | |
| Keywords | Tăng D-dimer, COVID-19 D-dimer, COVID-19 |
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