The value of morphology and cytochemistry via immunophenotyping in the diagnosis of childhood acute leukemia

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Abstract

ABSTRACT
Acute leukemia is the most commont cancer in children and is curable if correctly diagnosed and effectively treated. The diagnosis and accurate cloning of acute leukemia play an important role in the treatment resμlts for regimens and prognosis between two myeloid and lymphoid completely different. A descriptive cross- sectional study was carried out to compare the value of morphology and cytochemistry via immunophenotyping in the diagnosis of childhood acute leukemia. Research conducted from April 2017 to Jμly 2019 received 63 cases of patients diagnosed and treated at Pediatrics Center in Hue Central Hospital. The morphology was effective of AML and ALL were 92.1% and 95.2% respectively. The value of cytochemistry with Myeloperoxydase, Sudan black and P.A.S were 86% and 88%, 88.9% and 92.6%, 73.3% and 73.3% respectively. In current condition of developing countries, an effort to standardize morphology and cytochemistry woμld be cost – effective to immunophenotype for classification and differentiation of
acute leukemia.

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Published 24-01-2025
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Issue No. 56 (2019)
Section Original article
DOI
Keywords Key words: childhood acute leukemia, morphology, cytochemistry, immunophenotyping.

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Tuy, N. V., Viet, P. H., & Ha, C. V. (2025). The value of morphology and cytochemistry via immunophenotyping in the diagnosis of childhood acute leukemia. Journal of Clinical Medicine Hue Central Hospital, (56), 41–45. Retrieved from https://jcmhch.com.vn/index.php/home/article/view/706