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Abstract
Objective: Describe clinical and subclinical characteristics of Henoch-Schönlein purpura in children. Find the relationship between kidney lesion and clinical and subclinical manifestations.
Subjects and Methods: Cross-sectional descriptive study, including 51 children <15 years of age diagnosed with Schonlein-Henoch purpura being treated at Hue Central Hospital and Hue University Hospital from April 2016 - May 2018.
Results: 51 children entered the study: Male:Female =1.3:1; mean age 7.5 ± 3.4 years. At onset, purpura was present in all cases, gastrointestinal manifestations in 66.7%, arthritis/arthralgias in 54.9%, renal lesion in 19.6%. The most frequent laboratory abnormalities were Leukocytosis (WBC >10 x 109/L) in 60.8%, high-erythrocyte sedimentation rate (ESR) in 80.4%, microscopic hematuria in 15.7%, proteinuria in 13.7%. Renal lesion were correlated with age of onset. The age group> 10 years old has 6.1 times more kidney lesion than the group ≤ 10 years (OR: 6.1; 95% CI (1.5-26).
Conclusion: Clinical and subclinical findings of Schonlein-Henoch purpura in our study are similar to those in the literature. There is an relationship between the age of onset with kidney lesion
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| Published | 08-01-2025 | |
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| Issue | No. 60 (2020) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.2020.60.5 | |
| Keywords | ban Schonlein-Henoch, tổn thương thận Henoch-Schönlein purpura, kidney lesion. |
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