Abstract

Objectives: To evaluate exercise capacity using the 1-minute sit-to-stand test (1MSTST) and investigate factors related to the results of the 1MSTST in patients with chronic obstructive pulmonary disease (COPD).

Methods: A cross-sectional study was conducted on 61 stable COPD patients being hospitalized at Hue University of Medicine and Pharmacy Hospital. Clinical characteristics were collected, and the 1MSTST was performed. The data were analyzed to study factors related to the results of the 1MSTST.

Results: The average number of 1MSTST repetitions was 17.56 ± 6.76 times. The ≤60-year-old group showed better performance in the 1MSTST compared to the >60-year-old group. The COPD group A and B showed better performance in the 1MSTST compared to the COPD group E. The number of 1MSTST repetition decreased progressively from mMRC=0 to mMRC=4. The CAT <10 group showed better performance in the 1MSTST compared to the CAT ≥10 group. The CCQ total ≤3 group showed better performance in the 1MSTST compared to the CCQ total >3 group. There was an inverse correlation between 1MSTST performance and the following factors: disease duration (r = -0.338), number of COPD exacerbations requiring hospitalization per year (r = -0.346), mMRC (r = -0.669), CAT (r = -0.588), CCQ total (r = -0.592), CCQ symptoms (r = -0.419), CCQ functional state (r = -0.612), and CCQ mental state (r = -0.532). The results were statistically significant with p < 0.05.

Conclusion: The number of 1MSTST repetition was performed in patients >60 years old, patients had more symptoms, a higher exacerbation risk, and a longer disease duration, is significantly lower compared to patients ≤60 years old, patients had few symptoms, a lower exacerbation risk, and a shorter disease duration.