Abstract

Purpose: To explore the factors for recovery of renal function after surgery to remove unilateral ureteral stones. Method: There were 39 patients whounderwent contrast-enhanced computed tomography and renal scintigraphy to diagnose ureteral stones and determine the glomerular filtration rate and relative function of the ipsilateral kidney. The patient considers adrop in relative renal function of > 5% on renography. Characteristics of patients were evaluated such as ages, gender, calculus size, duration of obstruction, silent ureteral stones, symtomamtic ureteral stones, grade of hydronephrosis. Patientwere removed stones by ureterolithotripsy with laser Holmiumor retroperitoneal laparoscopy. All patientswere assessed postoperatively with exam serumcreatinine, urine culture andrenograms using technetium labeled (99m Tc) - diethylenetriamine pentaacetic acid (DTPA) and contrast computed tomography. We evaluated the change in serumcreatinine, glomerular filtration rate (GFR), renalfunction, ureteral stone - free and find association betweenrenal funtion recoverywith above factors. Statistical analysis was performed with SPSS 20.0.

Results: 39 patients met our inclusion criteria. Male/female: 14/25, mean age: 48.00 ± 13.59S tandard deviation(SD), BMI: 22.49 ± 1.88 SD. Ureteral stone - free is 100%. There was a change in plasma creatinine before and after operation 81,79 ± 18,59µmol/L and 66,70 ± 12,77µmol/L, p < 0,001. Change inpre - and postoperative glomerular filtration rate (GFR) of kidney diseases were34.90 ± 9.48 and 66.70 ± 12.77ml/min/1,73 m2 p < 0.001. Renal function recovery is 56.4%, no renal function recovery is 43,6%. The cut - off point ≤ 51 years ofage is a significant factor in the predictor of renal function recovery with a sensitivity of 72.7%, a specificity of 63.8%, (p < 0.01, area under curve: AUC = 0.738), the cut - off point of duration of obstruction ≤ 4 weeks is a significant factor in the predictor of renal function recovery with a sensitivity of 72.7%, a specificity of 64.7%, (p < 0.05, AUC = 0.695).

Conclusions: Glomerular filtration rate of the group kidney disease improved significantly from preoperatively to 3 months postoperatively. Duration of obstruction and the age of patientis related to the ability to recover kidney function.