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Abstract
Background: To evaluate the clinical efficacy of percutaneous vertebroplasty in the treatment of multiple osteoporotic vertebral compression fracture.
Materials and Methods: a prospective study of 32 patients presenting symptoms of pain and limitation in mobility with diagnosis of at least 2 acute vertebral compressions based on MRI. These patients then underwent percutaneous vertebroplasty. Post procedure, the clinical improvement factors including analgesic effects, motor function and quality of life were evaluated and followed up at 24th hours, 1, 3, 6, 12 months after the treatment.
Results: In our study, each patient underwent procedure had acute collapsed vertebrae ranged from 2 to 5 with total percutaneous vertebroplasty was 105. The early outcome of pain relief pre and post treatment in 24 hours based on VAS scale were 7.47±1.39 and 4.63±1.10 (p <0.001, respectively). Additionally, the improvement of motor function and life quality after treatment at 1-3-6-12 and >12 months were 0.52±0.20, 0.59±0.14, 0.67±0.12, 0.69±0.15, 0.68±0.18 compared to 0.83±0.10, 0.46±0.18, 0.36±0.15, 0.28±0.15, 0.26±0.18, 0.26±0.20, 0.16±0.17 before intervention (with p <0.001, respectively).
Conclusion: percutaneous vertebroplasty is an effective treatment for multiple osteoporotic vertebral compression fracture.
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| Published | 07-01-2025 | |
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| Issue | No. 67 (2021) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.2021.67.8 | |
| Keywords | Percutaneous vertebroplasty, osteoporotic vertebral compression fracture, multiple compression fracture, polymethylmetacrylat (PMMA) |
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