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Abstract
Background: Anaphylaxis is potentially fatal condition, and requires intensive care to reduce mortality rate, but the appropriate indication for continuous renal replacement therapy (CRRT) is controversial The objective of the study aimed to evaluate the prognostic factors for CRRT indications in children anaphylaxis at the PICU, National Children’s Hospital.
Methods: A case series study on110 patients with anaphylaxis from 1/1/2016 to 1/7/2021.
Results: Of the 110 patients evaluated, 21 (19.1%) required CRRT from January 2016 to July 2021. There was a statistically significant difference between CRRT indication and non - CRRT indication in heart rate, invasive systolic blood pressure (ISBP), pH, length of adrenalin infusion, HCO3-, lactate, vasoactive inotropic score (VIS), and PRISM III score (p < 0.05). Multivariable logistic regression demonstrated that SBP was an independent factor for CRRT indications in patients with anaphylaxis. The area under the receiver operating characteristic curve of the SBS was 0.741 (95% CI, P<0.05). The cut - off value of the ISBP was 75.5 mmHg (sensitivity 0.846, specificity 0.476).
Conclusions: SBP is an independent factor for indication of CRRT in anaphylactic shock patients.The cut - off value of the ISBP was 75.5 mmHg.
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| Published | 20-01-2023 | |
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| Issue | No. 84 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.84.6 | |
| Keywords | Sốc phản vệ, lọc máu, yếu tố tiên lượng, HATT Anaphylaxis shock, continuous renal replacement therapy, risk factor |
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