Evaluation of overall survival results on recurrent epithelial ovarian cancer treated with chemotherapy regimen peg liposomal Doxorubicin –Carboplatin at national cancer hospital

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Abstract

Objectives: Evaluating the overall survival resultsof the patients with receivedpegylated liposomal doxorubicin plus carboplatin regimen on recurrent epithelial ovarian cancer.

Methods: Retrospective and prospective study with 62 patients treated with pegylated liposomal doxorubicin - carboplatin regimen for platinum - sensitive recurrent epithelial ovarian cancer at National Cancer Hospital from January 2015 to January 2022.

Results: Median overall survival (OS) was 41,0 months (CI 95%: 35.9 - 46.1), median duration of progression free survival was 10.2 months (95% CI: 5.4 - 15). Median overall survival, progression free survival were correlated with platinum sensitivity.

Conclusion: The combined pegylated liposomal doxorubicin - carboplatin is the appropriate regimen in term of efficacy on patients with platinum sensitive recurrent epithelial ovarian cancer.

https://doi.org/10.38103/jcmhch.84.1

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Published 20-01-2023
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Language
Issue No. 84 (2023)
Section Original article
DOI 10.38103/jcmhch.84.1
Keywords Ung thư buồng trứng tái phát, nhạy platinum, CD Recurrent epithelial ovarian cancer, platinum-sensitive, CD

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Copyright (c) 2025 Journal of Clinical Medicine Hue Central Hospital

Le, T. D., & Nguyen, T. L. (2023). Evaluation of overall survival results on recurrent epithelial ovarian cancer treated with chemotherapy regimen peg liposomal Doxorubicin –Carboplatin at national cancer hospital. Journal of Clinical Medicine Hue Central Hospital, (84), 5–9. https://doi.org/10.38103/jcmhch.84.1