Outcomes of colorectal cancer with liver metastasis treated by radiofrequency ablation plus systemic chemotherapyat K hospital

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Abstract

Purpose: In this study, we evaluated the effectiveness of radiofrequency ablation with systemic chemotherapy in the treatment of colorectal cancer with liver metastasis at K hospital.
Methods: 30 patients with colorectal cancer liver metastasisin K hospital were etrospectively evaluated the effectiveness of radiofrequency ablation with systemic chemotherapy from January 2017 to August 2020.
Results: The responserate after 4 cycles and 8 cycles of chemotherapy was 73.3% and 85.2%, respectively. 100% of the patients had a tumor response after radiofrequency ablation. A complete response was 63.3%, and a partial response was 36.7% according to the International Intervention Photovoltaic Society standards. The progression - free survival was 16.7 ± 1.42 months. After radiofrequency ablation: all patients with mild to moderate hepatic pain, 10% of patients have fever, increased liver enzymes
encountered in 90% of patients

https://doi.org/10.38103/jcmhch.76.9

References

Abdalla EK, Vauthey J-N, Ellis LM, et al. Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases: Ann Surg. 2004;239(6):818-827.

Nguyễn Việt Long. Nghiên cứu kết quả bước đầu điều trị di căn gan trong ung thư đại trực tràng bằng đốt nhiệt sóng cao tần kết hợp hóa chất toàn

thân, luận án tiến sĩ y học. 2018

Goldberg SN, Charboneau JW, Dodd GD, et al. Image - guided Tumor Ablation: Proposal for Standardization of Terms and Reporting Criteria.

Radiology. 2003;228(2):335-345.

Ruers T, Punt C, Van Coevorden F, et al. Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004). Ann

Oncol. 2012;23(10):2619-2626.

Shady W, Petre EN, Gonen M, et al. Percutaneous Radiofrequency Ablation of Colorectal Cancer Liver Metastases: Factors Affecting Outcomes - A 10 - year Experience at a Single Center. Radiology. 2016;278(2):601-611.

Mulier S, Mulier P, Ni Y, et al. Complications of radiofrequency coagulation of liver tumours: Complications of radiofrequency coagulation of

liver tumours. Br J Surg. 2002;89(10):1206-1222.

Solbiati L, Livraghi T, Goldberg SN, et al. Percutaneous Radio - frequency Ablation of Hepatic Metastases from Colorectal Cancer: Long - term Results in 117 Patients. Radiology. 2001;221(1):159-166. doi:10.1148/ radiol.2211001624

Van Tilborg AAJM, Meijerink MR, Sietses C, et al. Long - term results of radiofrequency ablation for unresectable colorectal liver metastases: a

potentially curative intervention. Br J Radiol. 2011;84(1002):556-565.

Published 02-01-2025
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Language
Issue No. 76 (2022)
Section Original article
DOI 10.38103/jcmhch.76.9
Keywords Ung thư đại trực tràng, hóa chất, đốt sóng cao tần Colorectal cancer, chemotherapy, radiofrequency ablation

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Copyright (c) 2022 Journal of Clinical Medicine Hue Central Hospital

Tran, T., Vu, D. Q., & Hoang, T. C. (2025). Outcomes of colorectal cancer with liver metastasis treated by radiofrequency ablation plus systemic chemotherapyat K hospital. Journal of Clinical Medicine Hue Central Hospital, (76), 5–10. https://doi.org/10.38103/jcmhch.76.9