Abstract
Background: Upper urinary tract infection associated with obstruction is an emergent condition that needs proper and timely treatment. As the COVID-19 sees complicated development, the government has launched isolation and restriction orders to control the pandemic. This decision might drive more patients to defer medical care in comparison with the past. Therefore, we conduct this study to evaluate the upper urinary tract infection associated with obstruction presentations in Binh Dan hospital during the COVID-19 restriction period.
Methods: The data were collected from 150 patients who were hospitalized with diagnosis of upper urinary tract infection associated with obstruction during the peak outbreak of COVID-19 (from June to September 2021) and the corresponding period of the previous year. Unpaired Student’s t-test was utilized to compare continuous variables. Chi - square was used to investigate categorical data.
Results: Of 150 patients, 35 were admitted to hospital during the COVID-19 restriction order period. The number of hospitalized patients from June to September 2021 was remarkably lower than the corresponding time span of 2020. The rate of patients with SIRS in 2021 (54.2%) was significantly higher than that of 2020 (30.4%, p=0.01). However, there were no significant differences in terms of WBC count, GFR, grade of hydronephrosis and rate of usage of broad-spectrum antibiotics. There are no uroseptic shock cases or deaths recorded in 2021.
Conclusion: Despite a decrease in the number of hospital admissions, there was an increase in clinical severity of upper urinary tract infection associated with obstruction during COVID-19 outbreak in Ho Chi Minh city
References
Czeisler MÉ, Marynak K, Clarke KE, Salah Z, Shakya I, Thierry JM, et al. Delay or avoidance of medical care because of COVID-19–related concerns—United States, June 2020. Morbidity and mortality weekly report. 2020;69:1250.
Primessnig U, Pieske BM, Sherif M. Increased mortality and worse cardiac outcome of acute myocardial infarction during the early COVID‐19 pandemic. ESC heart failure. 2021;8:333-343.
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992;101:1644-1655.
Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama. 2016;315:801-810.
Tambo M, Okegawa T, Shishido T, Higashihara E, Nutahara K. Predictors of septic shock in obstructive acute pyelonephritis. World journal of urology. 2014;32:803-811.
Assimos D, Krambeck A, Miller NL, Monga M, Murad MH, Nelson CP, et al. Surgical management of stones: American urological association/endourological society guideline, PART I. The Journal of urology. 2016;196:1153-1160.
Borofsky MS, Walter D, Shah O, Goldfarb DS, Mues AC, Makarov DV. Surgical decompression is associated with decreased mortality in patients with sepsis and ureteral calculi. The Journal of urology. 2013;189:946-951.
Flukes S, Hayne D, Kuan M, Wallace M, McMillan K, Rukin NJ. Retrograde ureteric stent insertion in the management of infected obstructed kidneys. BJU international. 2015;115:31-34.
Pearle MS, Pierce HL, Miller GL, Summa JA, Mutz JM, Petty BA, et al. Optimal method of urgent decompression of the collecting system for obstruction and infection due to ureteral calculi. The Journal of urology. 1998;160:1260-1264.
Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M, et al. EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. Eur Urol. 2016;69:468-74.
Yamamoto Y, Fujita K, Nakazawa S, Hayashi T, Tanigawa G, Imamura R, et al. Clinical characteristics and risk factors for septic shock in patients receiving emergency drainage for acute pyelonephritis with upper urinary tract calculi. BMC urology. 2012;12:1-5.
Madanelo M, Ferreira C, Nunes‐Carneiro D, Pinto A, Rocha MA, Correia J, et al. The impact of the coronavirus disease 2019 pandemic on the utilisation of emergency urological services. BJU international. 2020;126:256-258.
Maringe C, Spicer J, Morris M, Purushotham A, Nolte E, Sullivan R, et al. The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study. The lancet oncology. 2020;21:1023-1034.
Motterle G, Morlacco A, Iafrate M, Bianco M, Federa G, Xhafka O, et al. The impact of COVID-19 pandemic on urological emergencies: a single-center experience. World journal of urology. 2021;39:1985-1989.
Naicker S, Yang C-W, Hwang S-J, Liu B-C, Chen J-H, Jha V. The novel coronavirus 2019 epidemic and kidneys. Kidney International. 2020;97:824-828.
Silva AB, Freschi G, Carrera RV, Astolfi RH, Berti FF, Gattas N, et al. COVID-19 pandemic impact on clinical outcomes of patients with obstructive pyelonephritis. International Urology and Nephrology. 2021;53:627-633.
Published | 02-01-2025 | |
Fulltext |
|
|
Language |
|
|
Issue | No. 81 (2022) | |
Section | Original article | |
DOI | 10.38103/jcmhch.81.8 | |
Keywords | Nhiễm khuẩn đường tiết niệu trên, bế tắc, cấp cứu, COVID-19 upper urinary tract infection, obtruction, emergency, COVID-19 |

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2022 Journal of Clinical Medicine Hue Central Hospital