Metastatic differentiated thyroid carcinoma with hyperthyroidism

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Abstract


Thyrotoxicosis in patients with metastatic thyroid cancer is very rare accounting for about <1% of all thyroid cancers metastasis. A definitive diagnosis needs to rule out several other causes of thyrotoxicosis such as lost
thyroid gland, functioning thyroid parenchyma, and overdose of thyroid hormones... The treatment has not had standard recommendations. However, reports suggested the role of synthetic antithyroid agents in the treatment of hyperthyroidism in metastatic thyroid cancer. Response to metastatic lesions with I - 131 is structurally poor and at the end of the treatment Tg concentration remains high despite the very strong I - 131 capture metastasis and patients may reach hypothyroidism. Progressive - free disease (PFS) and Overall survival (OS) in this group of patients are not currently reported due to rare occurrences. We reported two cases with manifestations of thyrotoxicosis with lesions that caught I - 131 outside the thyroid bed position after total thyroidectomy at the Military Institute of Radiological Medicine and Oncology.
Keywords: Metastatic thyroid cancer, hyperthyridism in thyroid cancer.

https://doi.org/10.38103/jcmhch.16.6.7

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Published 01-01-2025
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Language
Issue Vol. 16 No. 6 (2024)
Section Case report
DOI 10.38103/jcmhch.16.6.7
Keywords Từ khóa: Ung thư tuyến giáp di căn, nhiễm độc giáp trong ung thư tuyến giáp. Keywords: Metastatic thyroid cancer, hyperthyridism in thyroid cancer

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Copyright (c) 2024 Journal of Clinical Medicine Hue Central Hospital

Oanh, N. T. G. (2025). Metastatic differentiated thyroid carcinoma with hyperthyroidism. Journal of Clinical Medicine Hue Central Hospital, 16(6), 45–49. https://doi.org/10.38103/jcmhch.16.6.7