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Abstract
Background: Thyroid nodules are a commonly encountered clinical problem and are increasingly prevalent. The Bethesda thyroid cytopathology reporting system, established in 2017, aimed to guide pathologists and clinicians in determining appropriate treatment strategies. However, there remains inconsistency in treatment approaches, particularly in cases classified as Bethesda IV. This study aims to describe the ultrasound and histopathological characteristics of thyroid nodules classified as Bethesda IV, and investigate the risk factors associated with malignancy of thyroid nodules classified as Bethesda IV.
Method: A cross-sectional study on 70 patients who came for examination and treatment due to thyroid nodules at the Hospital of Hue University of Medicine and Pharmacy, from April 2023 to April 2024.
Results: The majority of patients with Bethesda IV thyroid nodules have a size of less than 2 cm (90,0%) and present with single nodules only (52,9%). According to the ACR-TIRADS classification system for thyroid nodule ultrasound results, the distribution is as follows: TIRADS 3 (17,1%), TIRADS 4 (62,9%), and TIRADS 5 (20,0%). The risk of postoperative malignancy for Bethesda IV thyroid nodules is 42,9%. Hypoechoic nodules, microcalcifications and TIRADS 5 result are predictive factors for malignancy risk in thyroid nodules, with adjusted odds ratios (aOR) of
4,7; 5,8 and 7.1, respectively.
Conclusions: Risk of malignancy of Bethesda IV thyroid nodules is 42,9%. Hypoechoic nodules, microcalcification and ACR-TIRADS 5 results are predictive factors for malignant thyroid nodules.
Keywords: Thyroid nodules, Bethesda IV, risk factors.
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| Published | 30-12-2024 | |
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| Issue | Vol. 16 No. 6 (2024) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.16.6.6 | |
| Keywords | Từ khóa: Nhân giáp, Bethesda IV, yếu tố nguy cơ. |
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