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Abstract
Objective: To investigate clinical, paraclinical characteristics and anemia rate in rheumatoid arthritis (RA) patients at Hue Central Hospital and explore some factors related to anemia (age, gender, BMI, disease duration, disease activity level, Iron, Ferritin and disease medication) in RA patients.
Methods: Patients age 16 and over, who treated at Internal Endocrinology - Musculoskeletal Department, Hue Central Hospital, were diagnosed with RA according to ACR/EULAR 2010 criteria. Collecting information about age, gender, BMI, disease duration, morning stiffness, number of swollen joints, and number of painful joints. All patients were evaluated by the following parameters: erythrocyte sedimentation rate, CRP, RF, X-ray, red blood cell count, peripheral reticulocyte count, MCV, MCH, MCHC, RDW, Hb, Ferritin and serum Iron.
Result: The rate of anemia according to Hb was 74.3%. Moderate anemia accounted for the majority (39.6%). Non - anemic, mild andsevere anemia were 25.7%, 33.7% and 1.0% respectively. The most common functional symptoms were reduced working capacity (17.3%), dizziness (20.0%), anorexia (14.7%). The common physical symptoms were pale skin, pale mucous membranes (80.0%), pale tongue 13.3%, hair loss 10.7%. Other symptoms were less common. The rate of increased Ferritin was 48.7%. The median Ferritin index was 365.3 (185.3 - 527.3). The rate of serum Iron reduction was 89.2%. The median serum Iron index was 4.1 (2.9 - 5.5). BMI, disease duration, Richie, DAS28, CRP, Iron were factors related to Hb with statistical significance (p < 0.05). Disease duration, CRP, iron were independently related factors with statistically significant Hb index (p < 0.05 to p < 0.001).
Conclusion: Anemia is common in RA and requires early detection, with appropriate treatment to improve the quality of life for patients.
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| Published | 29-12-2024 | |
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| Issue | No. 80 (2022) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.80.9 | |
| Keywords | Thiếu máu, viêm khớp dạng thấp, yếu tố liên quan Anemia, rheumatoid arthritis, associated factors |
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