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Abstract
Background: Prediabetes (PreDM) is defined as a health condition where blood glucose levels are higher than normal but not yet high enough to be diagnosed as diabetes. Approximately 25% of patients with PreDM will develop to overt type 2 diabetes mellitus within 3 - 5years. PreDM was also reported to increase the risk of macrovascular diseases and heart failure. Metabolic syndrome (MS) is characterized by abdominal obesity, dyslipidemia, hypertension, hyperglycemia, and is associated with an increased risk of developing cardiovascular disease, diabetes mellitus and other related diseases. There is remarkable link that is observed in recent studies between prediabetes and MS. The prevalence of MS in prediabetes has not been studied in Viet Nam. This study determine the prevalence of metabolic syndrome in the subjects. (2). Investigate metabolic syndrome and its associated factors in the study subjects.
Methods: A cross - sectional study with control group in 314 non - diabetic adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 160 patients with prediabetes and control group of 154 subjects with fasting blood glucose and HbA1c within the normal range.
Results: The prevalence of MetS in patients with prediabetes was 50% higher than control group (16,2%) (p < 0,001)). The prediabetes group had higher waist circumference, BMI, systolic blood pressure, diastolic blood pressure, glucose, insulin, HOMA-IR, total cholesterol, triglycerides, hs-CRP and lower HDL-C than the control group. Gender female, high systolic blood pressure, low HDL-C, and high triglycerides are independent risk factors for MetS in patients with prediabetes.
Conclusion: Metabolic syndrome was more prevalent in the prediabetic population in comparison to the normoglycemic individuals.
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| Published | 20-08-2023 | |
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| Issue | No. 89 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.89.17 | |
| Keywords | Hội chứng chuyển hóa, tiền đái tháo đường Metabolic syndrome, prediabetes. |
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