Giá trị xét nghiệm gene Xpert MTB/RIF đàm trong chẩn đoán lao phổi mới AFB(-)

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Abstract

Background: Direct sputum AFB test has low sensitivity, easy to miss AFB (-) pulmonary tuberculosis. Vietnam has deployed the Gene Xpert MTB/RIF test as a rapid diagnostic technique for tuberculosis. To evaluate the rate of new pulmonary TB AFB(-), survey and compare some characteristics with new pulmonary TB AFB(+); Determination of the sensitivity of Gene Xpert MTB/RIF test in the diagnosis of new pulmonary TB AFB(-).

Methods: Subjects were 328 new pulmonary tuberculosis patients, including 202 AFB(-) and 126 AFB(+), descriptive cross-sectional method.

Results: The rate of new pulmonary tuberculosis AFB(-) accounted for 61.58%. Compared with new pulmonary TB AFB(+): The rate of admission to other departmentsof new pulmonary TB AFB(-) is higher (20.09%, vs 11.11%: p < 0.01), lesions with cavernous lesions lower (30.20% vs 41.27%: p < 0.05), higher grade I lung injury (32.67% vs 20.63%: p < 0.05). The sensitivity of Gene Xpert MTB/RIF sputum test in the diagnosis of new pulmonary TB AFB(-) is 72.28%.

Conclusions: The sensitivity of Gene Xpert MTB/RIF sputum test in the diagnosis of new pulmonary TB AFB(-) is 72.28%.

 
https://doi.org/10.38103/jcmhch.89.8

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Published 29-12-2024
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PDF (Tiếng Việt)     138    30
Language
Issue No. 89 (2023)
Section Original article
DOI 10.38103/jcmhch.89.8
Keywords Lao phổi mới AFB(-), Gene Xpert MTB/RIF. : New pulmonary tuberculosis AFB(-), Gene Xpert MTB/RIF

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Copyright (c) 2023 Journal of Clinical Medicine Hue Central Hospital

Bính, P. T., & Phan Thị Phương, Hoàng Văn Long, Cao Thị Hồng Nguyễn Thị Bình Nguyên. (2024). Giá trị xét nghiệm gene Xpert MTB/RIF đàm trong chẩn đoán lao phổi mới AFB(-). Journal of Clinical Medicine Hue Central Hospital, (89). https://doi.org/10.38103/jcmhch.89.8