Abstract

Objectives: To investigate the characteristics of arrhythmias and parameters of heart rate variability by 24-hour Holter monitoring in patients after coronary intervention and evaluate the relationship of heart rate variability after coronary intervention to Syntax score, coronary artery injury characteristics and arrhythmias predictive value of heart rate variability.

Methods: A cross - sectional descriptive study on 50 patients admitted to the hospital with angina symptoms undergoing coronary angiography and coronary stenting at the International Center at Hue Central Hospital from April 2019 - October 2020.

Results: Proportion of arrhythmias were variable depending on each type: sinus arrest (8%), sinus bradycardia (18%), sinus tachycardia (12%), supraventricular extrasystoles (10%), extrasystoles ventricular tachycardia (64%), supraventricular tachycardia (30%). There was a reduction in time-domain and frequency - domain compared with normal values (p < 0.05). The mean NN and ln WF were related to the number of coronary branches damaged (p < 0.05). RMSSD (r = - 0.298), ln HF (r = - 0.288), pNN 50% (r = - 0.282) were negatively correlated with the SYNTAX scale (p < 0.05). The best cutoff for prognosis of arrhythmias of SDANN was ≤ 87ms with a sensitivity of 64.86% and a specificity of 69.23%. The best cutoff of SDNN was ≤ 99 ms with a sensitivity of 62.16% and a specificity of 69.23%. The best cutoff of lnVLF was ≤ 3.15 ms2 with a sensitivity of 56.76% and a specificity of 76.92%.

Conclusions: Patients with coronary artery disease after intervention were accompanied by arrhythmias and changes in heart rate variability. There is a relationship between heart rate variability with age and coronary artery damage. In addition, the heart rate variability is also capable of predicting cardiac arrhythmias in these patients.