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Abstract
Background: Neuroendocrine neoplasms (NENs) are a rare group of diseases comprising both benign and malignant tumors. Approximately 70% of NENs originate in the gastrointestinal tract; the majority run an indolent, asymptomatic course, while a small minority present with full-blown carcinoid syndrome. Rectal NENs are relatively rare, and definitive diagnosis relies on histopathology and immunohistochemistry. The mainstay of treatment involves surgery combined with systemic therapy, alongside the management of carcinoid symptoms using somatostatin analogs, interferon, mTOR inhibitors, tyrosine kinase inhibitors (TKIs), and chemotherapy. At the Department of Thoracic and Abdominal Surgery - Ho Chi Minh City Oncology Hospital, we describe the clinical, paraclinical, and histopathological characteristics, as well as provide an initial evaluation of treatment efficacy for 3 cases of rectal NENs, followed by a comparative correlation with current medical literature.
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| Published | 18-08-2026 | |
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| Issue | Vol. 18 No. 5 (2026) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.18.5.19 | |
| Keywords | tân sinh thần kinh nội tiết, bướu thần kinh nội tiết ở trực tràng neuroendocrine neoplasms, rectal neuroendocrine tumors |
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