Abstract

Objective: To evaluate atherogenic indices and the associations between these atherogenic indices and selected factors: body mass index (BMI), waist circumference, and physical activity in overweight and obese patients with prediabetes.

Methods: A Cross-sectional descriptive study on 104 overweight or obese patients with prediabetes treated at the Department of General Internal Medicine–Geriatrics, Hue Central Hospital, from June 2020 to Augus 2022.

Results: The prevalence of elevated TC/HDL-C was highest at 68.3%. Elevated TG/HDL-C and LDL-C/HDL-C accounted for 20.2% and 66.3%, respectively. 

Compared with the overweight group, the obese group had 1.1-fold higher odds of elevated TC/HDL-C and 1.5-fold higher odds of elevated LDL-C/HDL-C. Participants with increased waist circumference had 2.2-fold higher odds of elevated TG/HDL-C than those without increased waist circumference. Weak, statistically significant positive linear correlations were observed for: BMI with TC/HDL-C (r = 0.197), BMI with LDL-C/HDL-C (r = 0.280), Waist circumference with TC/HDL-C (r = 0.196). Waist circumference with TG/HDL-C (r = 0.283).

Conclusions: In overweight and obese adults with prediabetes, atherogenic dyslipidemia is common particularly elevated TC/HDL-C and LDL-C/HDL-C. Obesity increased the odds of elevated TC/HDL-C and LDL-C/HDL-C, and greater waist circumference was associated with higher TG/HDL-C