Abstract

Background: Diabetic kidney disease is a common complication of diabetes mellitus and a leading cause of chronic kidney disease and end-stage renal disease, requiring renal replacement therapy, including dialysis or kidney transplantation. Diabetic kidney disease also substantially increases cardiovascular morbidity and mortality and healthcare costs. This study aimed to determine the prevalence of reduced glomerular filtration rate and to investigate its association with selected factors among elderly patients with type 2 diabetes mellitus.

Methods: The study was conducted using a cross-sectional descriptive design involving 353 elderly patients with type 2 diabetes mellitus. Data were collected on age, sex, duration of diabetes, body mass index (BMI), glycemic control status, and estimated glomerular filtration rate.

Results: The mean age of the patients was 71.92 ± 7.28 years, with 45.04% female; 51.27% were overweight or obese, and 34.56% had a diabetes duration ≥10 years. The prevalence of reduced estimated glomerular filtration rate (eGFR) was 62.3%. Reduced glomerular filtration was significantly associated with age and duration of diabetes (p < 0.05), and was not associated with sex, overweight/obesity, or glycemic control (p > 0.05).

Conclusions: A reduced glomerular filtration rate is relatively prevalent among older adults with type 2 diabetes mellitus. Age and duration of diabetes were significantly associated with decreased glomerular filtration rate.