Characteristics of positive skin prick test reactions to respiratory allergens in hospitalized children with bronchial asthma
Original article | Vol. 18 No. 2 (2026)
Journal of Clinical Medicine Hue Central Hospital, Vol. 18 No. 2 (2026)
Original article

Characteristics of positive skin prick test reactions to respiratory allergens in hospitalized children with bronchial asthma

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Phu, N. M., Quan, H. D., Thinh, T. C. Q., Phuoc, B. V., Chi, P. T. B., Tho, N. H., … Tien, H. L. M. (2026). Characteristics of positive skin prick test reactions to respiratory allergens in hospitalized children with bronchial asthma. Journal of Clinical Medicine Hue Central Hospital, 18(2), 90–96. https://doi.org/10.38103/jcmhch.18.2.13
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DOI: 10.38103/jcmhch.18.2.13
10.38103/jcmhch.18.2.13
Nguyen Manh Phu
Pediatric Center, Hue Central Hospital
Ho Dang Quan
Pediatric Center, Hue Central Hospital
https://orcid.org/0009-0006-1285-8778
Tran Cong Quoc Thinh
Pediatric Center, Hue Central Hospital
https://orcid.org/0009-0004-2298-2540
Bui Van Phuoc
Pediatric Center, Hue Central Hospital
Phan Thi Bich Chi
Pediatric Center, Hue Central Hospital
Nguyen Huu Tho
Pediatric Center, Hue Central Hospital
Bui Binh Bao Son
Department of Pediatrics, University of Medicine and Pharmacy
Gerard Body
Etienne Bidat
Christine Castelain
Antoine Deschildre
Nguyễn Thị Diễm Chi
Ho Ly Minh Tien
Department of Pediatrics, Hue University of Medicine and Pharmacy

Abstract

Background: Bronchial asthma is a common chronic respiratory disease in children. Respiratory allergies account for 70-80% of disease onset causes. Skin prick test (SPT) is the gold standard diagnostic method for allergies. Vietnam lacks data on respiratory allergen patterns via SPT in hospitalized children with asthma, affecting diagnosis and treatment.

Methods: Cross-sectional descriptive study conducted from November 2023 to November 2024. A maximum of 63 children (age 5-15 years) with diagnosed stable bronchial asthma. SPT performed with 5-7 respiratory allergens (D. pteronyssinus, D. farinae, dog hair, cat hair, pollen, mold). Results analyzed using SPSS 20.0.

Results: 63 children with asthma (mean age 8±2 years, 55.6% male). Positive SPT rate: 52.4% (33/63). Most common allergens: D. pteronyssinus and D. farinae (39.7% each), cat hair (12.7%), dog hair (4.8%). 47.6% completely negative. In the group with previous asthma diagnosis history, the positive rate for D. pteronyssinus (44.2%) and D. farinae (46.2%) was significantly higher than those without history (18.2% and 9.1%, p<0.05). The D. pteronyssinus-positive group had a higher rate of complete control (60.9% vs 24.1%, p=0.018).

Conclusion: House dust mite allergens (D. pteronyssinus, D. farinae) are the most common respiratory allergens in asthmatic children in Hue. Previous asthma diagnosis history is strongly associated with house dust mite allergy. D. pteronyssinus allergy is associated with better asthma control.

Keywords:  asthma, skin prick test, respiratory allergens, children
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