Abstract

Objectives: To investigate the relationship between the atherogenic index of plasma (AIP) and the severity of coronary artery disease (CAD) as assessed by intravascular ultrasound (IVUS) in patients with acute myocardial infarction (AMI).

Methods: A cross-sectional descriptive study was conducted on 45 patients with acute myocardial infarction (AMI) at Hue Central Hospital from June to December 2024. All patients underwent coronary angiography and intravascular ultrasound (IVUS). Blood lipid parameters were collected within the first 24 hours of admission. Clinical, laboratory, and IVUS imaging data were analyzed to assess the correlation between the atherogenic index of plasma (AIP) and the characteristics of coronary artery lesions.

Results: AIP was positively correlated with the number of diseased coronary branches (r = 0.35, p = 0.02) and hs-TnT levels (r = 0.32, p = 0.03). HDL-C showed a negative correlation with the number of diseased branches (r = –0.42, p < 0.01). Minimal lumen area (MLA) was inversely related to plaque burden (r = –0.34, p = 0.02). Coronary calcification was significantly associated with a history of atherosclerotic cardiovascular disease and diabetes mellitus (p = 0.04).

Conclusion: AIP is a useful biomarker for predicting the severity of coronary artery involvement in AMI patients. These findings support its potential role in risk stratification and guiding interventional strategies in clinical practice.