Abstract

Objectives: To determine the 6-month all-cause mortality rate in patients with AHF after hospital discharge and evaluate the prognostic value of the BIOSTAT score for predicting all-cause mortality in this population.

Methods: A descriptive cross-sectional study with longitudinal follow-up was conducted on patients aged ≥18 years who were discharged with a diagnosis of AHF from Thong Nhat Cardiovascular Center between January 2024 and December 2024. All patients were followed for 6 months post-discharge for the outcome of all-cause mortality.

Results: A total of 309 patients aged ≥18 years diagnosed with AHF were included. The 6-month all-cause mortality rate was 18.77%. Among these, 83.17% had a BIOSTAT score between 0 and 3 (BIOSTAT scores of 0, 1, 2, and 3 accounted for 16.50%, 20.39%, 24.60%, and 21.68%, respectively), while 16.83% had a BIOSTAT score between 4 and 5 (BIOSTAT scores of 4 and 5 were 11.97% and 4.85%, respectively). Compared with patients having BIOSTAT scores of 0–3, those with scores of 4–5 had a significantly higher hazard ratio (HR) for all-cause mortality: 1.84 (p = 0.03). The area under the ROC curve (AUC) was 0.838.

Conclusion: A higher BIOSTAT score (4–5 points) was significantly associated with increased risk of mortality (p < 0.05). The area under the ROC curve (AUC) was 0.838.