Research on the effectiveness and safety of interventional techniques for extracranial internal carotid artery lesions in patients with acute ischemic stroke due to tandem occlusion
Original article | Vol. 17 No. 1 (2025)
Journal of Clinical Medicine Hue Central Hospital, Vol. 17 No. 1 (2025)
Original article

Research on the effectiveness and safety of interventional techniques for extracranial internal carotid artery lesions in patients with acute ischemic stroke due to tandem occlusion

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Phu, H. H., Toan, N. D., Binh, L. T., Anh, T. D., Minh, L. N. N., Minh, K. N., … Toan, H. Q. (2025). Research on the effectiveness and safety of interventional techniques for extracranial internal carotid artery lesions in patients with acute ischemic stroke due to tandem occlusion. Journal of Clinical Medicine Hue Central Hospital, 17(1), 5–10. https://doi.org/10.38103/jcmhch.17.1.1
HTML (Tiếng Việt)     547    40
PDF (Tiếng Việt)     547    234
DOI: 10.38103/jcmhch.17.1.1
10.38103/jcmhch.17.1.1
  • Hoang Hai Phu
  • Nguyen Dinh Toan
  • Le Trong Binh
  • Tran Duc Anh
  • Le Nguyen Ngoc Minh
  • Kim Nhat Minh
  • Tran Thanh Tu
  • Huynh Quoc Toan
Hoang Hai Phu
https://orcid.org/0009-0008-1883-1044
Nguyen Dinh Toan
Le Trong Binh
https://orcid.org/0000-0001-5444-5708
Tran Duc Anh
Le Nguyen Ngoc Minh
Kim Nhat Minh
Tran Thanh Tu
Huynh Quoc Toan

Abstract

Introduction: Acute ischemic stroke caused by large vessel occlusion is a severe condition, especially when multiple lesions result in cerebral vascular occlusion. This study was conducted to evaluate the effectiveness and safety of interventional techniques for extracranial internal carotid artery lesions in patients with acute ischemic stroke due to tandem occlusion.

Methods: This is a prospective, non-randomized study, evaluating patients before and after treatment.

Results: There were no significant differences in the clinical and imaging characteristics between the carotid stenting group and the balloon angioplasty group. The stenting group showed high efficacy in restoring blood flow, with a TICI score ≥ 2b achieved in 94.1% of cases, compared to 90% in the balloon angioplasty group. The NIHSS score improvement from hospital admission to 24 hours post-treatment was 8.5 ± 3.2 in the stenting group, which was not significantly higher than 5.3 ± 6.9 in the balloon angioplasty group. At the 3-month follow-up, 94.1% of patients in the stenting group had a mRS score of 0-2, compared to 50% in the balloon angioplasty group. Both techniques presented a low incidence of complications, with no significant differences between the two groups.

Conclusion: Interventional techniques for extracranial internal carotid artery lesions in patients with acute ischemic stroke due to tandem occlusion yield positive outcomes. However, stenting shows better prognostic results at 3 months compared to simple balloon angioplasty.

Keywords:  Large vessel occlusion, tandem occlusion, emerency carotid artery stenting
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