Study on plasma Osteocalcin concentration in elderly men with metabolic syndrome

Downloads

Download data is not yet available.

Supplementary Files

PDF (Tiếng Việt)     0    0

Abstract

Objectives: To determine plasma Osteocalcin concentration in elderly men ( 70 years old) with metabolic syndrome. Survey on the correlation between plasma Osteocalcin levels and the components of metabolic syndrome according to the criteria of International Diabetes Federation (IDF).

Subjects and methods: A descriptive, cross-sectional study on 100 elderly men. We select 50 men with metabolic syndrome at the Examination Department, Hue Central Hospital as patients group and 50 healthy men without metabolic syndrome as control group. All person were measured height, weight, BMI, waist circumference, blood pressure, fasting plasma glucose, bilan lipid.  

Results: The average concentration of Osteocalcin in group with metabolic syndrome were 19.64±8.30 ng/mL lower than those without metabolic syndrome (25.47±12.88 ng/mL). In the group with metabolic syndrome, Osteocalcin levels in group with increased triglycerid were 17.02±6.08 ng/mL lower than those without increased triglycerid (31.61±6.35 ng/mL). Osteocalcin levels had inversely correlated with waist circumference, plasma glucose, triglycerid.

Conclusions: The average concentration of Osteocalcin in elderly men with metabolic syndrome group were lower than those without metabolic syndrome. Osteocalcin levels was inversely correlated with waist circumference, plasma glucose, triglycerid.

References

Alfadda Assim A, Afshan Masood, Shaffi Ahamed Shaik et al (2013), "Association between Osteocalcin, Metabolic Syndrome, and Cardiovascular Risk Factors: Role of Total and Undercarboxylated Osteocalcin in Patients with Type 2 Diabetes", International Journal of Endocrinology, 20: 13, Article ID 197519:

Chillarón Juan J, Juana A Flores-Le Roux, David Benaiges, Juan Pedro-Botet (2014), "Subclinical cardiovascular disease in type 2

diabetes mellitus: To screen or not to screen", World J Clin Cases, 2(9): 415-421.

Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G (2007), "Endocrine regulation of energy metabolism by the skeleton", Cell, 130(3): 456-69.

Misao Arimatsu, Takao Kitano, Naoko Kitano, Makoto Futatsuk (2009), "Correlation between bone mineral density and body composition in Japanese females aged 18-40 years with low forearm bone mineral density", Environ Health Prev Med, 14: 46-51.

Ravn P, Cizza G, Bjarnason NH, Thompson D, Daley M, Wasnich RD, McClung M, Hosking D, Yates AJ, Christiansen C (1999), "Low body

mass index is an important risk factor for low bone mass and increased bone loss in early post menopausal women", Journal of bone and mineral Research, 14(9): 1622-1627.

Scherer PE (2006), "Adipose tissue: From lipid storage compartment to endocrine organ", Diabetes, 55: 1537-1545.

Yeap Bu B, S A Paul Chubb, Leon Flicker et al (2010), "Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels", European Journal of Endocrinology, 163: 265-272.

Zimmet Paul, George Alberti, Jonathan Shaw (2005), "A new IDF worldwide definition of the metabolic syndrome: the rationale and the results", Diabetes Voice, 50(3): 31-33.

Published 07-09-2015
Fulltext
Language
Issue No. 30 (2015)
Section Original article
DOI
Keywords Osteocalcin, nam giới cao tuổi Osteocalcin, elderly men

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2025 Journal of Clinical Medicine Hue Central Hospital

dinhloihv@gmail.com, & Hoang Thi Thu Huong, Le Thi Phuong Anh, Tran Huu An, Ton That Ngoc. (2015). Study on plasma Osteocalcin concentration in elderly men with metabolic syndrome. Journal of Clinical Medicine Hue Central Hospital, (30), 42–48. Retrieved from https://jcmhch.com.vn/index.php/home/article/view/2210