Abstract
Objectives: To assess some factors that affected on the platelet aggregation with ADP and to investigate correlations between some hematological indexes with platelet aggregation with ADP.
Methods: A prospective, cross-sectional study of 32 healthy adults, aged from 18 to 35 years, regardless of gender, agreed to participate in Hematology and Blood Transfusion Department, Military Hospital 103.
Results: Mean value of platelet aggregation with ADP was 70.1%. There was no gender difference of platelet aggregation with ADP at sample collection time (TO) (p>0.05). After 6 hours (T6), platelet aggregation with ADP decreased significantly compared with TO and T4 (p<0.001). Samples using 3.8% sodium citrate tube showed lower platelet aggregation with ADP compared with 3.2% sodium citrate tube (p<0.001). The platelet aggregation showed no difference between normal platelet count (150-450 G/l) and > 450 G/l platelet countof platelet-rich plasma. The platelet aggregation with ADP correlated strongly with mean platelet volumm (MPV) of peripheral blood (r=−0,687 p<0,005). There was no correlation between platelet aggregation with ADP and other hematological indexes of peripheral blood (p>0.05).
Conclusions: The results of platelet aggregation with ADP were influenced by time, anticoagulant, MPV and they were not influenced by gender and platelet count of platelet-rich plasma
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| Published | 31-10-2017 | |
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| Issue | No. 42 (2017) | |
| Section | Original article | |
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| Keywords | yếu tố ảnh hưởng, ngưng tập tiểu cầu, ADP impact factors, platelet aggregation, ADP |
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