Evaluation of the treatment of retinoblastoma at ophthalamology department in HCH 2009- 2015

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Abstract

Purpose: To describe the clinical characteristics and evaluate the outcome of retinoblasma treatment at Ophthalmology Department in HCH from 2009 to 2015. Methods: A retrospective study in 19 eyes of 16 children with retinoblastoma were treated at the Ophthalmology Department in HCH from 2009 to 2015 Results: A mean age was 39.69 months. The primary reason was "white pupillary reflex" (81.25%). Tumor's representation in one eye was 81.25%, and two eyes was 18.75%. 17/19 eyes were removed the eyeball, 2/19 eyes were had preservatived treatment. The pathological results of 100% enucleated eyes were retinoblastoma. 94.12% cases had not signs of optic nerve invasion. 5 patients (31.25%) were treated by chemotherapy combination. One death. Conclusions: Retinoblastoma was detected late. Tumor's representation in one eye was 81.25%, and two eyes was 18.75%. The incidence in male more than female (7/1). The ratio of the eyeball removing was high (89.48%). The mortality rate was 6.25%.

References

Balmer A, Zografos L, Munier F (2006), "Diagnosis and current management of retinoblastoma", Oncogene, 25(38): 5341-5349.

Đỗ Hương Giang (2013), Nhận xét đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị u nguyên bào võng mạc tại Bệnh viện K, Luận văn tốt nghiệp Bác sỹ đa khoa, Đại học Y Hà Nội.

Phạm Thị Việt Hương và cộng sự (2009), “Nhận xét đặc điểm lâm sàng, cận lâm sàng và hiệu quả của phác đồ EC trong điều trị bảo tồn bệnh u nguyên bảo võng mạc tại bệnh viện K”, Tạp chí Ung thư học Việt Nam, Số chuyên đề nhân dịp kỷ niệm 40 năm thành lập Bệnh viện K 1969-2009, Hội phòng chống ung thư Việt Nam, tr. 16-21.

Hyery Kim, Ji Won Lee (2008), "Clinical Results of Chemotherapy based Treatment in Retinoblastoma Patients: A Single Center Experience", Cancer Res Treat., 40(4): 164-171.

Nguyễn Công Kiệt, Nguyễn Trí Dũng (2006), “Khía cạnh di truyền của 61 ca ung thư nguyên bào võng mạc tại bệnh viện Mắt TP HCM từ 11/2003 đến

(2012) Trung ương”, Tạp chi Nhãn khoa Việt Nam, 36, tr. 3-12.

Kivela T (2009), "The epidemiological challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death", British Journal of Ophthalmology, 93(9); 1129-1131.

Lê Thúy Quỳnh, Nguyễn Minh Châu, Trần Thu Hương (2014), "Đánh giá đặc điểm lâm sàng và kết quả điều trị bệnh nhân ung thư võng mạc tại khoa mắt trẻ em Bệnh viện Mắt 11/2005", Tạp chí Y học TP HCM, 1, tr. 23-29.

Rachma Mee, Venkatraman Radhakrishnan (2012), "Current therapy and recent advances in the management of retinoblastoma", Indian J Med Paediatr Oncol, 33(2): 80-88.

Shields CL, Shields J.A (2004), "Diagnosis and management of retinoblastoma", Cancer Control, 11(5): 317-327.

Shields CL, Shields J.A (2006), "Basic understanding of current classification and management of retinoblastoma", Curr Opin Ophthalmol, 17(3): 228-234

Published 06-03-2025
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Issue No. 28 (2015)
Section Original article
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Keywords u nguyên bào võng mạch, thị thần kinh retinoblastoma, optic nerve

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Nhu Vinh Tuyen, P., Ngoc Hai An, L., Hoang An, D., Nha Uyen, P., & Le Ngoc Khanh, N. (2025). Evaluation of the treatment of retinoblastoma at ophthalamology department in HCH 2009- 2015. Journal of Clinical Medicine Hue Central Hospital, (28), 54–59. Retrieved from https://jcmhch.com.vn/index.php/home/article/view/2146