Evaluation of clinical and paraclinical features in patients with carcinoma of oral cavity histopatology feature of oral cavity carcinoma

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Abstract

Background: Oral carcinoma is one of the most common cancers of the head and neck region. It is one of the eight most common cancers according to the World Health Organization (WHO), the incidence of which will increase in the future. Although the means of diagnosis and treatment have developed, the prognosis is still poor, mainly due to regional lymph node metastasis.

Materials and Methods: From July 2015 to July 2016, 32 patients with carcinoma of the oral cavity at Hue Central Hospital

Results: The most common age group is from 51 to 60 years old and the male/female ratio is 1.9/1. Tumor places are usually observed around the the tongue (40.6%) and oral floor (34.4%). Most of the tumor size is larger than 2 cm diameters (> 80%). The regional lymph node metastasis rate is 43,8% and there is a positive correlation between lymph node metastasis and tumor sizea (p < 0,05). Squamous - cell carcinoma is mainly type of histopathology. Difference between the rate of lymph node metastasis in patient groups with different histopathological grade shows no statistical significance (p > 0,05).

Conclusion: The greater tumor becomes, the higher regional lymph node metastasis rate increase. There is no relationship between lymph node metastasis rate and histopathological grade of oral carcinoma.

https://doi.org/10.38103/jcmhch.2021.73.5

References

Giang NTH, Nghiên cứu đặc điểm lâm sàng, mô bệnh học và nhận xét một số yếu tố nguy cơ ung thư biểu mô khoang miệng tại Bệnh viện K. 2002, Trường Đại học Y Hà Nội: Hà Nội.

Feller L, Lemmer J. Oral Squamous Cell Carcinoma: Epidemiology, Clinical Presentation and Treatment. Journal of Cancer Therapy. 2012.

: 263-268.

Pires FR, Ramos AB, Oliveira JB, Tavares AS, Luz PS, Santos TC. Oral squamous cell carcinoma: clinicopathological features from 346 cases from a single oral pathology service during an 8-year period. J Appl Oral Sci. 2013. 21: 460-7.

Marchiano E, Patel TD, Eloy JA, Baredes S, Park RC. Impact of Nodal Level Distribution on Survival in Oral Cavity Squamous Cell Carcinoma: A Population - Based Study. Otolaryngol Head Neck Surg. 2016. 155: 99-105.

Tường PN. Khảo sát tỷ lệ và đặc điểm bệnh nhân ung thư biểu mô vảy đầu - cổ tại Bệnh viện Trung ương Huế Tạp Chí Y Học Lâm Sàng. 2018. 50: 9 - 15.

Kademani D, Bell RB, Bagheri S, Holmgren E, Dierks E, Potter B, et al. Prognostic factors in intraoral squamous cell carcinoma: the influence

of histologic grade. J Oral Maxillofac Surg. 2005. 63: 1599-605.

Woolgar JA. Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma. Oral Oncol. 2006. 42: 229-39.

Thanh HTV, Nghiên cứu điều trị ung thư biểu mô khoang miệng có sử dụng kỹ thuật tạo hình bằng vạt rãnh mũi má. 2013, Trường Đại học Y Hà Nội: Hà Nội.

El - Naggar AK, Chan JK, Grandis JR, WHO classification of head and neck tumours. 2017.

Mackay J. JA, Clee N., et al., in The cancer Atlas. 2006, American Cancer Society. p. 206-230.

Phạm Nguyên Tường PP, Nguyễn Thanh Ái Ung thư khoang miệng: chẩn đoán và điều trị tại khoa Ung bướu bệnh viện Trung Uơng Huế trong 5 năm (1999 - 2003). Y học Việt Nam. 2004. số đặc biệt: 141-151.

Anneroth G, Batsakis J, Luna M. Review of the literature and a recommended system of malignancy grading in oral squamous cell

carcinomas. Scand J Dent Res. 1987. 95: 229-49.

Juliana noguti cfgdm, gustavo protasio pacheco de jesus, victor hugo pereira dasilva, thaisayako hossaka, celina tijuko fujiyama oshima,

daniel araki ribeiro. Metastasis from Oral Cancer: An Overview CANCER GENOMICS &PROTEOMICS 2012. 9: 329-336

Published 02-03-2025
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Language
Issue No. 73 (2021)
Section Original article
DOI 10.38103/jcmhch.2021.73.5
Keywords Ung thư biểu mô khoang miệng, kích thước u, di căn hạch, mô bệnh học Carcinoma of oral cavity, tumor size, lymph node metastasis, histopathology

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Copyright (c) 2021 Journal of Clinical Medicine Hue Central Hospital

Loi, N. H., & Minh, N. V. (2025). Evaluation of clinical and paraclinical features in patients with carcinoma of oral cavity histopatology feature of oral cavity carcinoma. Journal of Clinical Medicine Hue Central Hospital, (73), 29–34. https://doi.org/10.38103/jcmhch.2021.73.5