Six cases of appendiceal cancer: Literature review, diagnosis and treatment

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Abstract

Appendiceal cancer is a very rare disease. Based on 6 cases of appendiceal cancer
who were admitted to the Internal Medicine of Breast, Gastroenterology, Hepatology,
Urology, Department, Oncology Hospital of Ho Chi Minh City from September 2019 to
March 2021, we evaluate the available literature review about diagnosis and treatment
of appendiceal cancer. Four out of 6 cases were diagnosed with stage IV disease,
only 1 case was in stage II, and 1 case with undermined stage. All cases were treated
with Capecitabine-based chemotherapy, 5 out of 6 were treated with Capecitabine and
Oxaliplatin combination, while the other was treated with Capecitabine monotherapy.
We didn’t use hyperthermic intraperitoneal chemotherapy in any of those cases
because of technical limitations at Ho Chi Minh City Oncology Hospital. Up to the time
of reporting, all 6 cases are being monitored for survival

https://doi.org/10.38103/jcmhch.78.2

References

McCusker ME et al. Primary malignant neoplasms of the appendix: A population-based study from the surveillance, epidemiology and end-results program, 1973-1998. Cancer. 2002; 94:3307-3312.

Sugarbaker PH. New standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome. Lancet Oncol. 2006; 7:69-76.

Ji H, et al. Cytokeratins 7 and 20, Dpc4, and MUC5AC in the distinction of metastatic mucinous carcinomas in the ovary from primary ovarian mucinous tumors: Dpc4 assists in identifying metastatic pancreatic carcinomas. Int J Gynecol Pathol. 2002; 21:391-400.

Levine EA, et al. Prognostic molecular subtypes of low-grade cancer of the appendix. J Am Coll Surg. 2016; 222:493-503.

Pai RK, et al. Appendiceal mucinous neoplasms: Clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol. 2009; 33:1425-1439.

Nutu OA, Manrique Municio A, Justo Alonso I, Calvo Pulido J, García-Conde M. Tumores mucinosos del apéndice: incidencia, diagnóstico y tratamiento quirúrgico. Cir Esp. 2017; 95:321-327.

Leiting J.L., et al. The impact of HIPEC vs. EPIC for the treatment of mucinous appendiceal carcinoma: a study from the US HIPEC collaborative. International Journal of Hyperthermia. 2020; 37(1):1182-1188.

Wang G, Li Q, Chen W. Chemotherapy in the treatment of different histological types of appendiceal cancers: a SEER-based study. BMC Cancer. 2021; 21(1):778.

Copur M.S., et al. Mucinous Adenocarcinoma of the Appendix With Histologic Response to Neoadjuvant Chemotherapy: Review of Histologic and Clinical Spectrum of Epithelial Neoplastic Mucinous Lesions of the Appendix. ONCOLOGY. 2021; 35(6):335-340.

Carr NJ et al. Epithelial non-carcinoid tumors and tumor-like lesions of the appendix. A clinicopathologic study of 184 patients with a multivariate analysis of prognostic factors. Cancer. 1995; 75:757-768.

Glasgow SC, et al. The American Society of Colon and Rectal Surgeons, Clinical Practice Guidelines for the Management of Appendiceal Neoplasms. Diseases of the Colon & Rectum. 2019; 62:1425-1438.

Lu Y, et al. Clinicopathological Features of Low-Grade Appendiceal Mucinous Neoplasms Confined to the Appendix. Frontiers in Oncology. 2021; 11.

Chen W, Ye JW, Tan XP et al. A case report of appendix mucinous adenocarcinoma that recurred after additional surgery and a brief literature review. BMC Surg. 2020; 20:182.

Hoehn RS et al. Current Management of Appendiceal Neoplasms. American Society of Clinical Oncology Educational Book. 2021; 41:118-132.

Dulskas A et al. Long-Term Outcomes after Surgery for Appendiceal Mucinous Tumours. Visceral Medicine. 2018; 34(2):151-155.

Published 25-03-2022
Fulltext
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Issue No. 78 (2022)
Section Case report
DOI 10.38103/jcmhch.78.2
Keywords Appendiceal cancer, diagnosis, chemotherapy Appendiceal cancer, diagnosis, chemotherapy

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Copyright (c) 2022 Journal of Clinical Medicine Hue Central Hospital

Luong, H. T., Phan, T. H. D., & Tran, N. H. (2022). Six cases of appendiceal cancer: Literature review, diagnosis and treatment. Journal of Clinical Medicine Hue Central Hospital, (78), 9–12. https://doi.org/10.38103/jcmhch.78.2