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Abstract
Objectives: To evaluate the results of breast conserving surgery (BCS) and intraoperation radiation therapy (IORT) on breast cancer patients at Hue Central Hospital.
Methods: This retrospective descriptive study was conducted on 91 breast cancer patients who were at stages T1N0M0 - T2N0M0, tumor size less than 3cm and underwent BCS and IORT at Hue Central Hospital from 2014 to August 2022.
Results: The average age of patients was 48.2 ± 9.3 years old. Patients with tumor size T1 accounted for 62.9%.Patients with pN0 accounted for 94.3%. There were 76 pathological results invasive ductal carcinoma accounted for 85.4%. Patients in the Luminal A group accounted for the highest percentage (57.3%). After 5 years, there were 13 patients with relapse, accounting for 14.6%. The mean DFS was 103.5 ± 3.3 months (95% CI = 97.0 - 109.9). DFS for 5 years at 85.4%. The mean overall survival was 110.2 ± 1.8 months. Overall 5 - year survival of the whole study group was estimated at 95.5%. DFS in T1 group, negative lymph nodes higher than in T2 group, positive lymph nodes. This difference is statistically significant, p < 0.05, but not statistically significant when comparing the age factor older or younger than 40, p = 0.72. OS in the T1 group, negative lymph nodes, age > 40, higher in group T2, positive lymph nodes, and age < 40. This difference was statistically significant, p < 0.05.
Conclusion: Breast preserving surgery and intraoperation radiation therapy is safe, effective and necessary operation for early breast cancer treatment.
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| Published | 26-12-2024 | |
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| Issue | No. 91 (2023) | |
| Section | Original article | |
| DOI | 10.38103/jcmhch.91.14 | |
| Keywords | Ung thư vú giai đoạn sớm, phẫu thuật bảo tồn, xạ trị trong mổ, thời gian sống còn không bệnh, thời gian sống còn toàn bộ Early breast cancer, breast concerving surgery, intraoperative radio - therapy, disease - free survival, overall survival |
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