Abstract
Purpose: To evaluate the diagnostic values of fine needle aspiration (FNA) in patients with cervical lymphadenopathy.
Methods: A descriptive research of patients with enlarged cervical lymph nodes excisionally biospied in three years 2019 - 2022 at Oncology Department, Hospital of Hue University of medicine and pharmacy were studied retrospectively.
Results: Preoperative firm density evaluation in clinical examination correlated well with the malignant cervical lymph nodes (p = 0,037), but this clinical evaluation may not predict well the patients with tuberculous nodes (p > 0,05). Geographic traits of patients had no relation with tuberculous lymph nodes. Overall, fine needle aspiration can predict correctly 52/59 cases about 88,1% and miss diagnose 11,9% cases of cervical lymphadenopathy. Sensitivity and specificity value of FNA in malignant prediction of cervical lymph nodes were 76,5% and 90,5% respectively with p < 0,05. Nevertheless, fine needle aspiration could not predict accurately tuberculous lymph nodes with low sensitivity 56% and specificity 70,5%.
Conclusion: Palpation in clinical exmination and fine needle aspiration are two valuable approaches in diagnosing malignant cervical lymphadenopathy, should be used routinely. However, those procedures could not replace excisional biopsy in diagnosis of tuberculous lymph nodes.
References
Mehrotra R, Singh M, Gupta RK, Singh M, Kapoor AK. Trends of prevalence and pathological spectrum of head and neck cancers in North India. Indian J Cancer. 2005; 42(2): 89-93.
Fatima S, Arshad S, Ahmed Z, Hasan SH. Spectrum of cytological findings in patients with neck lymphadenopathy-experience in a tertiary care hospital in Pakistan. Asian Pac J Cancer Prev. 2011; 12(7): 1873-5.
Hirachand S, Lakhey M, Akhter J, Thapa B. Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu Univ Med J (KUMJ). 2009; 7(26): 139-42.
NCCN. B cell lymphoma. 2023; 05.2023:[Available from: https://www.nccn.org/professionals/physician_gls/pdf/bcell.pdf.
Balm AJ, van Velthuysen ML, Hoebers FJ, Vogel WV, van den Brekel MW. Diagnosis and treatment of a neck node swelling suspicious for a malignancy: an algorithmic approach. Int J Surg Oncol. 2010; 2010: 581540.
Xu D, Xu HM, Li MK, Chen LY, Wang LJ. Feasibility of fine-needle aspiration biopsy and its applications in superficial cervical lesion biopsies. Int J Clin Exp Pathol. 2014; 7(8): 5165-70.
Nesreen H. Hafez NST. Reliability of fine needle aspiration cytology (FNAC) as a diagnostic tool in cases of cervical lymphadenopathy. Journal of the Egyptian National Cancer Institute. 2011; 23(3): 105-114.
Nguyễn Phước Bảo Quân c. Nghiên cứu giá trị của siêu âm và siêu âm hướng dẫn chọc hút tê bào bằng kim nhỏ hạch cổ di căn trong ung thư thực quản. Tạp chí điện quang Việt Nam. 2013(12).
Mitra S, Ray S, Mitra PK. Analysis of FNAC of cervical lymph nodes: experience over a three-year period. J Indian Med Assoc. 2013; 111(9): 599-602.
Bazemore AW, Smucker DR. Lymphadenopathy and malignancy. Am Fam Physician. 2002; 66(11): 2103-10.
Knox J, Lane G, Wong JS, Trevan PG, Karunajeewa H. Diagnosis of tuberculous lymphadenitis using fine needle aspiration biopsy. Intern Med J. 2012; 42(9): 1029-36.
Asimacopoulos EP, Berry M, Garfield B, Roesner M, Jepson A, McCarthy J, et al. The diagnostic efficacy of fine needle aspiration using cytology and culture in tuberculous lymphadenitis. Int J Tuberc Lung Dis. 2010; 14(1): 93-8.
Published | 26-12-2024 | |
Fulltext |
|
|
Language |
|
|
Issue | No. 91 (2023) | |
Section | Original article | |
DOI | 10.38103/jcmhch.91.9 | |
Keywords | Hạch cổ, lao hạch, phương pháp chọc hút bằng kim nhỏ, giá trị chẩn đoán Cervical lymphadenopathy, Fine needle aspiration, diagnostic value |

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2023 Journal of Clinical Medicine Hue Central Hospital