Downloads
Abstract
The experience in treating nephroblastoma at Hue Central Hospital Objective: Evaluation of effectiveness of surgical treatment combined with chemo-radio therapy of nephroblastoma.
Material and methods: Prospective collected data from 25 patients with nephroblastoma who underwent surgical treatment combined with chemo-radio therapy at Hue Central Hospital from January 2010 to January 2016.
Result: Age average 42.3 months, male/female 1.27/1, the most common symptom was abdominal mass with 96%, in 64% of the cases the tumor occured on the right side, in 36% on the left side. 72% of the patients were treated with National Wilms Tumor Study Protocol, 28% of the patients were treated with International Society of Paediatric Oncology Protocol. Average operating time was 120±25 minutes. The duration of hospitalization was 6.2±0.3 days. 28% of the patients were pathologically diagnosed with favorable histology, 56% with intermediate histological and 16% of the patients with unfavorable histology. Recurrence rate was 12% in the first year, death rate 8%. Survival rate after 2 years was 92%.
Conclusion: Surgical treatment combined with chemo-radio therapy of nephroblastoma is safe and effective.
References
Nguyễn Thanh Liêm (2002), Ung thư nguyên bào thận, Phẫu thuật tiết niệu trẻ em, Nhà xuất bản Y học, Hà Nội.
Nguyễn Bửu Triều (2007), U nguyên bào thận, Bệnh học tiết niệu, Nhà xuất bản Y học, Hà Nội.
Abrew M. Davidoff (2013), Wilms tumor, Adv Pediatr, 59(1), pp: 247-267.
Sushmita Bhatnagar (2009), Management of Wilms’ tumor: NWTS vs SIOP, J Indian Assoc Pediatr Surg, 14(1), pp: 6-14.
Joseph M. Gleason, Armando J. Lorenzo, Paul R. Bowlin, Martin A. Koyle (2014), Innovations in the management of Wilms’ tumor, Ther Adv Urol, 6(4), pp: 165-176.
Robert C. Shamberger, James R. Anderson, Norman E. Breslow, Elizabeth J. Perlman, et al. (2011), Long-Term Outcomes of Infants with Very Low Risk Wilms Tumor Treated with Surgery Alone on National Wilms Tumor Study -5, Ann Surg, 251(3), pp: 555-558.
Sabina Szymik-Kantorowicz, Wiesław Urbanowicz, Marcin Surmiak, Janusz Sulisławski (2012), Therapeutic results in stage I Wilms’ tumors in children – 15 years of surgical experience, Cent European J Urol, 65(3), pp: 151-155.
R. C. Shamberger, K. A. Guthrie, M. L. Ritchey, G. M. Haase, J. Takashima, J. B. Beckwith, G. J. D’Angio, D. M. Green, N. E. Breslow (1999), Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study 4, Ann Surg, 229(2), pp: 292-297.
So-Young Lee, Kyu-Rae Kim, Jung-Yeol Park, Jae Y. Ro (2012), Wilms’ Tumor with Long-delayed Recurrence: 25 Years after Initial Treatment, Korean J Urol, 53(4), pp: 288-292.
B. Guruprasad, B. Rohan, S. Kavitha, D. S. Madhumathi, D. Lokanath, L. Appaji (2013), Wilms’ Tumor: Single Centre Retrospective Study from South India, Indian J Surg Oncol, 4(3), pp: 301-304.
| Published | 19-08-2016 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | No. 36 (2016) | |
| Section | Original article | |
| DOI | ||
| Keywords | nephroblastoma, chemo-radio therapy |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Journal of Clinical Medicine Hue Central Hospital