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Abstract
Background: Burkholderia cepacia is a gram - negative bacillus and the causative agent of opportunistic infections, with various clinical manifestations. However, deep vein thrombosis following Burkholderia cepacia infection is rarely reported in the literature. We reported a case of deep vein thrombosis of the lower extremity with diabetic ketoacidosis after B. cepacia infection to describe the characteristics of the case and compare the literature with cases of B. cepacia infection accompanied by venous thrombosis.
Case report: An 80 - year - old male patient was admitted to the hospital with fever, lethargy, and shortness of breath for 2 days. Initial investigation showed diabetic ketoacidosis and the patient was treated according to the regimen. During the treatment, localized swelling of the left leg was noted, and the patient was later diagnosed with deep vein thrombosis of the left lower extremity. The culture of his blood grew B. cepacia and the patient was administrated with antibiotics (Ceftazidime in combination with Trimethoprim/Sulfamethoxazole) according to the antimicrobial susceptibility testing and anticoagulation for venous thrombosis. However, even after intensive appropriately treatment, the patient deteriorated rapidly, and died 2 weeks after admission.
Conclusion: In patients infected with B. cepacia infection, venous thromboembolism screening tests should be performed promptly if clinically suspected to provide an appropriate treatment strategy.
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| Published | 22-12-2024 | |
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| Issue | No. 94 (2024) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.94.15 | |
| Keywords | Burkholderia cepacia, huyết khối tĩnh mạch sâu. |
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