Study of relationship between cardiovascular risk factors, mehran score and contrast - associated acute kidney injury

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Abstract

Background: Contrast - associated acute kidney injury which is one of the major complications of percutaneous coronary intervention (PCI) can be prevented if it is predicted through risk factors. In recent years, researchers suggest many risk scores to determine the risk of contrast - induced acute kidney injury such as: Mehran risk score, the ratio between the amount of contrast, and estimated GFR. So we implement the study to find out the relationship between cardiovascular risk factors and contrast - associated acute kidney injury

Objects: 221 patients who were diagnosed with coronary disease and treated by PCI.

Methods: Prospective observational study.

Results: Hypotension during the procedure is a independent risk factor of contrast-associated acute kidney injury with OR = 5,299, 95%CI 1,177-23,854 (p = 0,030). NT-proBNP is is a independent risk factor of contrast-associated acute kidney injury with OR = 1,000, 95%CI 1,000-1,000 (p = 0,018). Mehran score for the high risk patients (11-15 points) is an independent risk factor of contrast-associated acute kidney injury with OR = 7,983, 95%CI 1,080-58,990 (P = 0,042). Mehran score for the very high risk patients (≥ 16 points) is an independent risk factor of contrast-associated acute kidney injury with OR = 53,821, 95%CI 3,046-951,033 (P = 0,007).

Conclusion: Intraoperative hypotension, NT-proBNP, Mehran score in high and very high risk groups are independent risk factors of contrast-associated acute kidney injury.

Keywords: Mehranscore, acute kidney injury, contrast, coronary artery

https://doi.org/10.38103/jcmhch.2021.71.1

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Published 18-02-2025
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Issue No. 71 (2021)
Section Original article
DOI 10.38103/jcmhch.2021.71.1
Keywords Điểm nguy cơ Mehran, tổn thương thận cấp, thuốc cản quang, động mạch vành Mehranscore, acute kidney injury, contrast, coronary artery

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Copyright (c) 2021 Journal of Clinical Medicine Hue Central Hospital

Nghia, B. X., Bao, H. B., & Binh, H. A. (2025). Study of relationship between cardiovascular risk factors, mehran score and contrast - associated acute kidney injury. Journal of Clinical Medicine Hue Central Hospital, (71), 3–11. https://doi.org/10.38103/jcmhch.2021.71.1